Episode 27: Behind the Paper: Sequential NRP and NMP in DCD Liver Transplantation | Behind the Paper

In this episode of Behind the Paper, Macey Levan, Social Media Editor for the Transplantation journals, speaks with Rohit Gaurav, FRCS, about his article:

Sequential In Situ Normothermic Regional Perfusion and Ex Situ Normothermic Machine Perfusion in Controlled Donation After Circulatory Death Liver Transplantation: A Retrospective Single-center Experience

The discussion focuses on the use of sequential normothermic regional perfusion, or NRP, and normothermic machine perfusion, or NMP, in controlled donation after circulatory death liver transplantation.

Dr. Gaurav explains how DCD livers have historically presented challenges due to hypoxia, ischemia, and biliary complications, and how NRP and NMP can help transplant teams assess organ function and improve liver utilization.

The episode explores lactate clearance, liver enzyme assessment, post-reperfusion outcomes, biliary complications, and the role of machine perfusion in expanding the safe use of DCD organs. Dr. Gaurav also discusses how implementation of these techniques has increased DCD liver utilization at his center and how this approach is shaping broader practice in the United Kingdom.

Read the article: https://journals.lww.com/transplantjournal/abstract/10.1097/tp.0000000000005659~sequential-in-situ-normothermic-regional-perfusion-and-ex?redirectionsource=fulltextview

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