PsychEd: Educational Psychiatry Podcast

PsychEd Episode 54: Cannabis and Psychosis with Dr. Nitin Chopra

PsychEd: Educational Psychiatry Podcast

Show Notes

Welcome to PsychEd - the psychiatry podcast for medical learners, by medical learners. This episode covers the relationship between cannabis and psychotic disorders, as well as the potential impact of cannabis legalization in Canada, with our special guest Dr. Nitin Chopra. This episode was originated by Dr. Luke Fraccaro for his Grand Rounds.

The learning objectives for this episode are as follows: By the end of this episode, you should be able to… Briefly summarize the effects of cannabis on mental health and cognition, with a focus on psychosis.

Appreciate the evidence for cannabis use as a potential cause of persistent psychotic disorders.

Discuss the possible impact that recent cannabis legislation may have had on cannabis use and psychosis in Canada.

Guest Expert Dr. Nitin Chopra is an addictions psychiatrist at the Centre for Addiction and Mental Health (CAMH) and is an Assistant Professor in the Department of Psychiatry at the University of Toronto. He has an interest in concurrent disorders and is a staff psychiatrist on the Concurrent Addictions Inpatient Treatment Service and Concurrent Outpatient Medical and Psychosocial Addiction Support Service. Through his work on the Psychiatry Addictions Capacity Building and Consultation Service (PACCS) at CAMH and the Addiction Medicine and Psychosocial Addictions ECHO program, he is evolving into a leader in capacity building and education for addictions treatment. Furthermore, Dr. Chopra also works on the Early Psychosis Unit at CAMH and has extensive clinical experience working with patients experiencing psychosis, often with comorbid cannabis and other substance use.

Grand Rounds Presenter: Dr. Luke Fraccaro (PGY3)

Produced by: Dr. Luke Fraccaro (PGY3), Dr. Alex Raben (staff psychiatrist), and Josh Benchaya (MS4)

Hosts: Dr. Luke Fraccaro (PGY3), Dr. Alex Raben (staff psychiatrist), and Josh Benchaya (MS4)

Audio Editing by: Dr. Luke Fraccaro (PGY3)

Show notes by: Dr. Luke Fraccaro (PGY3)

Conflicts of Interest: There are no known conflict of interests to report

Topics: 0:00 - Introduction

2:50 - Objectives

3:55 - Case example

7:25 - Overview of cannabis effects of mental health

10:45 - Differentiating clinically between cannabis-induced psychosis and a primary psychotic disorder

13:11 - Cannabis causing acute psychotic symptoms

14:15 - Back to the case

16:05 - Overlapping risk factors for cannabis use and psychotic disorders

18:14 - Cannabis use as a potential cause of persistent psychotic disorders (Reviewing the evidence)

30:14 - Summary of the relationship between cannabis and psychosis and how to apply it clinically

35:20 - Cannabis legalization in Canada

39:45 - Canadian studies on potential impact of cannabis legalization on psychosis

44:33 - Brief review of American studies on potential impact of cannabis legalization on psychosis.

46:35 - Summary of potential impact of legalization

47:42 - Questions and discussion

1:06:15 - Summary and Outro

Resources: Canada’s Lower-Risk Cannabis Use Guideline: https://www.camh.ca/-/media/files/lrcug_professional-pdf.pdf

Cannabis legalization and regulation in Canada: https://www.canada.ca/en/health-canada/programs/engaging-cannabis-legalization-regulation-canada-taking-stock-progress/document.html

References: American Psychiatric Association: Diagnostic and Statistical Manual of Mental Disorders: Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition, Text Revision. Arlington, VA: American Psychiatric Association, 2022.

Tourjman SV, Buck G, Jutras-Aswad D, Khullar A, McInerney S, Saraf G, Pinto JV, Potvin S, Poulin MJ, Frey BN, Kennedy SH, Lam RW, MacQueen G, Milev R, Parikh SV, Ravindran A, McIntyre RS, Schaffer A, Taylor VH, van Ameringen M, Yatham LN, Beaulieu S. Canadian Network for Mood and Anxiety Treatments (CANMAT) Task Force Report: A Systematic Review and Recommendations of Cannabis use in Bipolar Disorder and Major Depressive Disorder. C

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