
The Man Who Invented Klotho & FLGR-242 – Michael Farber Pt. 1 | Peptide of the Week Podcast
Peptide of the Week | Weight Loss, Health & WellnessShow Notes
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Medical Disclaimer: We are not doctors. The content in this video is for educational and informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Any compounds discussed may be intended for research purposes only. Use at your own risk.
This is not a conversation about peptides. This is a conversation with the man who invented two of the most talked about longevity compounds on the planet. Dr. Michael Farber joins JD Denham and William T. Haas to break down Klotho and FLGR-242 from the ground up. Who created them, why he created them, how they actually work in the body, and where medicine is heading in the next 20 years.
🔬 Topics Covered: • Who is Dr. Michael Farber and his 35 years in biochemistry and 150 patents • Why he invented Klotho to save his own kidney after losing his right kidney in his teens • How Klotho regulates phosphate and calcium and why that matters for kidney function • The feedback loop of kidney disease that has never been reversible until now • People going from an EGFR of 40 back up to 70 and beyond on Klotho • Why Klotho makes NAD work dramatically better through the SIRT1 pathway • Klotho and the blood brain barrier: clearing toxic plaque buildup without entering the brain • Why Dr. Farber considers Klotho more important for longevity than FLGR-242 • How the albumin binder platform works and why it allows bi-weekly dosing • Klotho dosing: 10 micrograms every two weeks for healthy individuals, every 11 to 12 days for kidney dysfunction • What happens if you overdose Klotho and why it is strictly range-bound • FLGR-242: the long-acting myostatin inhibitor that is outperforming all expectations • Why FLGR-242 dosing is nothing like Follistatin-344 and must not be confused • The future of medicine: synthetic organs, CRISPR, fetal genetic optimization, and living to 120 • Dr. Farber consumed a bottle of painkillers a week for decades. In the last 18 months he has taken two or three total.
Chapters: 00:00 – Cold Open: Living With Kidney Disease for 40 Years 00:45 – Intro 00:54 – Welcome Back & Meeting Dr. Michael Farber 02:50 – Why He Created Klotho: Losing a Kidney 05:10 – Klotho Results: 10 mcg & Rising eGFR 07:34 – The Albumin Binder Breakthrough 12:28 – How Klotho Works in the Body 14:53 – Klotho, NAD+ & FLGR-242 Synergy 20:13 – Cardiovascular Health & Restored Libido 21:54 – Klotho Dosing: 10 mcg Every 11–14 Days 24:52 – Separating Hype From Reality 27:14 – Overdose Risks & Checking Urine Output 29:42 – Feeling "Reborn": Life After Kidney Disease 36:30 – The Future of Longevity: Organs & CRISPR 45:12 – Outro & Part 2 Preview
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More from Peptide of the Week | Weight Loss, Health & Wellness
Follow us on social media: JD's Instagram: https://www.instagram.com/jddenhamofficial/ Will's Instagram: https://www.instagram.com/williamthaas/ Peptide Of The Week Socials: https://hoo.be/peptideoftheweekpodcast
Follow us on social media: JD's Instagram: https://www.instagram.com/jddenhamofficial/ Will's Instagram: https://www.instagram.com/williamthaas/ Peptide Of The Week Socials: https://hoo.be/peptideoftheweekpodcast
Follow us on social media: JD's Socials: https://hoo.be/jddenhamofficial Will's Socials: https://hoo.be/williamthaas Peptide Of The Week Socials: https://hoo.be/peptideoftheweekpodcast
Follow us on social media:JD's Instagram: https://www.instagram.com/jddenhamofficial/Will's Instagram: https://www.instagram.com/williamthaas/Peptide Of The Week Socials: https://hoo.be/peptideoftheweekpodcast Join The Community: https://www.skool.com/peptideresearchinstitute/about Subscribe to our Newsletter: https://potwnewsletter.beehiiv.com/ Warrior Coaching: https://www.warrior-makerscoaching.com Peptide Of The Week Website: https://peptideoftheweekpod.com Medical Disclaimer: We are not doctors. The content in this video is for educational and informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Any compounds discussed may be intended for research purposes only. Use at your own risk. JD Denham and William T. Haas are China bound for a peptide trade show and vendor tour. Before they head out, they sit down for a full Q&A covering anaphylaxis fear around common peptides, a terrifying Tesamorelin reaction that may have been a cardiac event, the ultimate first responder protocol, washout periods, HGH timing for law enforcement on two hours of sleep, Winstrol vs FLGR 242, overdosing 5-Amino-1-MQ, and why a 22-year-old running 300mg of test weekly needs to hear some hard truth. 🔬 Topics Covered• Is the anaphylaxis risk from Tesamorelin and MOTS-C actually as high as people claim?• Left arm pain and sweating after a Tesamorelin injection: cardiac event or bad batch?• The ultimate year-long peptide protocol for firefighters and first responders• How long should you actually take off between peptide cycles?• HGH timing for a cop waking up at 2am: morning, night or both?• Does caffeine or pre-workout actually blunt your HGH response?• Winstrol vs Masteron vs Primo: which cutter is actually worth it?• Why FLGR 242 is making JD look like he is on a steroid cycle without actually being on one• 10mg of 5-Amino-1-MQ sub Q: total waste of money or actually dangerous?• A 22-year-old on 300mg of test, R, HCG and Anavar: the honest conversation they needed to hear Chapters:00:00 – Cold Open: Why Bodies React So Differently00:44 – Intro00:53 – Welcome Back & China Business Trip04:44 – Getting Help for Addiction & Giving Back06:51 – School, VIP Perks & Coaching Updates10:24 – Q&A: Anaphylaxis Risk With Tesamorelin, Ipamorelin & MOTS-c17:11 – Q&A: Chest Pain & Sweating After Tesamorelin22:00 – Q&A: First Responder Year-Round Stack32:32 – Q&A: How Long a Washout Period Between Stacks37:39 – Q&A: Best Time to Take HGH With a 2 AM Workout45:04 – Q&A: Is 10 mg of 5-Amino-1MQ Worth It?47:55 – Q&A: Winstrol, Test Dosing & Leaning Out59:48 – Q&A: TRT, HCG & Tesamorelin at 221:11:34 – Outro & Gear Podcast Idea
JD's Socials: https://hoo.be/jddenhamofficialWill's Socials: https://hoo.be/williamthaasPeptide Of The Week Socials: https://hoo.be/peptideoftheweekpodcast Join The Community: https://www.skool.com/peptideresearchinstitute/aboutSubscribe to our Newsletter: https://potwnewsletter.beehiiv.com/Warrior Coaching: https://www.warrior-makerscoaching.comPeptide Of The Week Website: https://peptideoftheweekpod.com Medical Disclaimer: We are not doctors. The content in this video is for educational and informational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Any compounds discussed may be intended for research purposes only. Use at your own risk. Most people know GHK-Cu. Very few know AHK-Cu. JD Denham and William T. Haas break down both copper peptides, how they differ, how to stack them, and why one of them may be the most underrated hair growth compound available right now. 🔬 Topics Covered:• What GHK-Cu actually is and how it was discovered• How GHK-Cu rebuilds collagen types 1, 2, and 3• Why copper levels in your body drop 50% by age 60 and what that means for your skin• The copper uglies: what to expect in the first two weeks and why you should push through• Injectable vs topical vs shampoo: which to use and when• Why you cannot overdose on the Wolverine stack the way you can when copper is in the blend• Laser facial recovery cut in half using the GHK-Cu face serum• Snap-8: why it is called Botox in a bottle and why it belongs in your serum• Microneedling protocol for face and scalp: how to do it right• What AHK-Cu is and how it differs from GHK-Cu• The three things AHK-Cu does inside the hair follicle• Hair growing back darker on AHK-Cu: what people are reporting• Why JD's folliculitis makes him the perfect use case for running both• Brand new GHK-Cu plus AHK-Cu shampoo blend: what to expect• Dosing protocol for both: 2.5mg total copper, 2 to 3x per week injectable• Why nighttime is the best time to inject healing peptides Chapters:00:00 – Cold Open: GHK-Cu & Laser Facial Healing00:50 – Intro00:59 – Welcome Back & Mold Update05:07 – Today's Compounds, School & VIP Zoom Call Updates08:32 – GHK-Cu: The Copper Peptide Explained10:56 – Benefits: Anti-Aging, Wound Healing & Scars12:29 – Injectable vs. Topical vs. Shampoo14:53 – How to Use It: Laser Facials & Microneedling17:35 – Fun Facts: "Copper Uglies" & Injection Sting19:49 – What to Avoid & Best Stacks24:19 – AHK-Cu: How It Grows Hair29:14 – Hair Transplants, DHT & Non-Hormonal Benefits35:15 – Dosing Protocols40:12 – FLGR-242, Clotho & Why Insulin Is Dangerous44:20 – Outro & Coaching Updates