Show Notes
Over 400,000 of you have used my AI chat app since it went live. I don’t read your individual messages. But the app sends me an anonymized report of what people struggle with most. So I took the top questions from the last week and answered them myself.We start with mitochondria. I walk through how I rotate SS-31, MOTS-c and SLU-PP-332. I also explain why I think a lot of people who stall on a GLP-1 have a mitochondrial problem. Then we hit reconstitution math, cloudy vials, and why some peptides sting.From there it’s growth hormone. Tesamorelin alone versus the tesamorelin and ipamorelin blend, plus what to do when it wrecks your sleep. On the GLP side I cover how I raise my retatrutide dose and use taurine for the heart rate bump. Then how I step down without the appetite rebound.We also get into where to inject BPC-157, my actual favorite sleep peptides, and free versus total testosterone. Plus the hormone targets I like for women in perimenopause.I close with fertility. After years on TRT, I went from zero sperm to the top of the reference range in nine months. I walk through the exact stack I used. Your questions, my honest answers.For research and entertainment purposes only. Subscribe for more peptide research and analysis.👇 ALL MY LINKS IN ONE PLACEhttps://hunterwilliamshealth.com/links00:00 Intro and where these questions come from04:26 Stacking SS-31, MOTS-c and SLU-PP-33206:03 SS-31 fasted or with food06:33 Where 5-amino-1MQ fits with TRT07:18 NAD and 5-amino in one syringe07:41 Can Cartalax help bone on bone08:34 LL-37 with CJC or MOTS-c09:01 Reconstituting KLOW and GLOW blends10:00 Cloudy vial, is it ruined10:39 Best syringes and needles11:22 Why some peptides sting12:21 Tesamorelin alone vs tesa/ipa blend14:28 Tesamorelin timing and sleep15:06 Tesamorelin to CJC and ipamorelin15:39 Ipamorelin 5 on, 2 off16:08 HGH and IGF-1 LR3 timing17:37 Protecting muscle off a GLP-118:37 How to titrate GLP-3 RT19:51 GLP-3 RT heart rate bump20:48 GLP-3 RT back to GLP-2 TZ22:00 Stepping down off a GLP-123:36 Eloralintide, amylin and GLP-1s24:52 GLP-3 RT side effects and breaks25:32 Where to inject BPC-15726:34 How long to run KLOW27:30 KPV before BPC-157 and TB-50028:08 BPC-157 and TB-500 in one syringe28:21 Favorite sleep peptides and DSIP29:34 When Semax does nothing30:08 Calming inflammation without growth30:57 Free vs total testosterone31:24 Restarting natural testosterone31:44 Testosterone injections vs cream32:45 Testosterone targets in perimenopause33:54 PT-141 and women's libido34:34 Labs to get and how often35:47 Kisspeptin, enclomiphene and HCG for fertility36:50 Wrap up
More from The Hunter Williams Podcast
Most people know oxytocin as the love hormone. That’s only a small part of the story.In this masterclass I break down what I’ve learned using oxytocin myself and digging through 70 years of human data. It was the first peptide hormone ever made in a lab.
All links here: https://hunterwilliamshealth.com/links
Samantha Lander is one of the most compelling voices in functional health and peptide coaching, and her path to getting here is unlike anyone else in the space.
Most people treat IGF-1 LR3 like a muscle peptide you just add to the cart. I want to slow that down a bit.In this masterclass I break down IGF-1 LR3 and IGF-1 DES. Both are modified versions of the IGF-1 your liver makes. They work by dodging the binding proteins that keep most of your IGF-1 parked and inactive. More free IGF-1 means more signal actually reaching the muscle.I cover who these make sense for and who should skip them. I walk through my dosing tiers, starting at 40 to 50 micrograms. We get into timing around training, why you always dose with carbs on board, and the day my wife and I ended up buying candy mid-workout.I also explain why your IGF-1 blood work might drop while you run these. Plus the feedback loop behind it, why I cycle four to six weeks, and how I stack them with TRT and growth hormone.One honest note. There are zero human trials on either compound. Most of the data comes from rats and cell cultures, and the rest is experience, mine included.Done right, these are a five to ten percent edge on top of a solid foundation. That’s it, and that’s still worth having.For research and entertainment purposes only. Subscribe for more peptide research and analysis.👇 ALL MY LINKS IN ONE PLACEhttps://hunterwilliamshealth.com/links
Dr. Tyna Moore is one of the most censored voices in the peptide and HRT space. She’s a naturopathic doctor with decades of clinical experience in regenerative medicine and was one of the first practitioners advocating for intelligent, individualized use of GLP-1s before it was mainstream. Instagram silenced her in 2024 right as the conversation was heating up. Today she’s here to set the record straight. We get into the origins of GLP-1 micro dosing, the LDN analogy that actually explains it, how censorship twisted her message into a vanity weight loss narrative, and why she believes GLPs are one of the greatest longevity tools we have. We also cover HRT for perimenopausal women, retatrutide, injectable joint therapies, and things that have never been discussed publicly before. Topics covered: GLP-1 micro dosing explained, LDN vs GLP-1 mechanism, how censorship shaped the narrative, canc3r and COVID data, retatrutide for perimenopausal women, HRT before or after GLP, the 35% weight loss study, joint health and when BPC-157 stops working, prolotherapy and PRP, tachyphylaxis and the blast and cruise model, estrogen receptors in the brain, and what your partner’s TRT could be doing to your hormones. Connect with Dr. Tyna Moore: Website: drtyna.com Community: skool.com/drtyna Instagram: instagram.com/drtyna Connect with Hunter: hunterwilliamshealth.com/links ⚠️ This podcast is for research and educational purposes only. Nothing discussed constitutes medical advice. Always consult a licensed healthcare professional before making any changes to your health protocol.