The Proof with Simon Hill

Superagers, statins, the latest cholesterol pill and the truth about heart disease risk | Dr Terry Simpson

The Proof with Simon Hill

Show Notes

Dr Terry Simpson is back, and we go deep on the science of protecting your heart and brain for the long run. He is a surgeon and one of the clearest voices online for separating solid evidence from confident hype, and in this conversation we tackle everything from new cholesterol-lowering drugs to gene editing, cognitive ageing, and the lean mass hyperresponder debate.

Along the way we get a few things off our chests about the misinformation that spreads faster than the careful answer ever can.

What We Cover

Why healthy ageing brains owe more to lifestyle than to genetics

How PCSK9 inhibitors work, and why plaque is more like geology than plumbing

Gene editing for cholesterol and functional cures for type 1 diabetes

The lean mass hyperresponder debate and what the Keto-CTA re-analysis shows

Why colorectal cancer is rising in younger adults

The 2026 dyslipidemia guidelines and why you should test your Lp(a) once

This is a grounded, evidence-first conversation, and I hope it helps you feel clearer and more confident about the decisions that actually move the needle. If you enjoy the episode, please take a moment to rate and review the show, it genuinely helps more people find it.

To connect with Dr Terry Simpson, visit terrysimpson.com, where you will find his bio, recipes, and plenty more. You can also follow him on Instagram, X, and TikTok, and read his writing on Substack.

Want to support the show?

The best way to support the show is to use the products and services offered by our sponsors. To check them out and enjoy great savings, visit theproof.com/friends. You can also support the show by leaving a review on the Apple Podcast app and sharing your favourite episodes with friends and family.

This episode is brought to you by:

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Simon Hill, MSc, BSc (Hons)

Creator of theproof.

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