BIOACTIVE

Cannabis and Real World Data with Dr. Miyabe Shields

BIOACTIVE

Show Notes

Dr. Riley Kirk welcomes Dr. Miyabe Shields for a deep dive into cannabis real-world data, cannabis consumption patterns, dosing, neurodivergent cannabis use, and the Endocannabinoid System (ECS). As co-founders of the Network of Applied Pharmacognosy (NAP), Riley and Miyabe discuss the newly accessible Real Data Project, including what large-scale consumer data can reveal about how people actually use cannabis in their everyday lives.

They explore why terms like “heavy cannabis consumption” are difficult to define, how consumption can vary by dose and frequency, and what the data shows across different populations and consumption methods. They also discuss the importance of making real-world cannabis data accessible to consumers, researchers, patients, and healthcare professionals rather than keeping it behind academic paywalls or within highly controlled research settings.

The conversation also covers cannabis and neurodivergence, cannabis and mental health, the challenges of interpreting cannabis research, product chemistry and consumer experiences, terpene levels, cannabis aging, and how chemical data can eventually be connected with the way individual consumers actually feel after using a product.

Finally, Riley and Miyabe discuss their ECS-focused e-book, created to make information about the Endocannabinoid System more accessible to both new and experienced cannabis consumers, including practical information about dosing, lifestyle, sleep, exercise, diet, and understanding your own ECS.

Chapters

00:00 Giveaway!

00:53 Welcome to another NAP Time episode

01:27 What is the Real Data Project?

03:00 Why “heavy cannabis consumption” is difficult to define

04:25 Dose, frequency, and different types of cannabis consumers

06:05 What the consumption data is beginning to reveal

09:20 Real-world data on cannabis-infused beverages

11:39 Cannabis use and neurodivergent populations

14:27 What the data can and cannot tell us

17:45 Cannabis research, stigma, and risk factors

19:13 Barriers to cannabis as medicine

23:09 Real-world data vs. clinical trials and meta-analyses

29:45 Why cannabis chemistry alone doesn't tell the whole story

34:41 Making cannabis data accessible to everyone

39:00 How cannabis aroma preferences change over time

41:26 Terpenes, harshness, and the importance of mouthfeel

47:49 Connecting product chemistry with real-world effects

49:15 What happens to cannabis as it ages?

51:46 Explore the Real Data Project

52:26 A new Endocannabinoid System e-book

58:14 Building research with community feedback

59:06 What Miyabe and Riley are consuming right now

01:02:14 Final thoughts

Resources

Explore the Real Data Project / RWD Exchange:

https://rwdexchange.com/

Network of Applied Pharmacognosy (NAP):

https://www.appliedpharmacognosy.org/

E-book Update

We really hope the e-book is ready by the time this episode airs, but we’re still working on finalizing the graphics! Once the e-book is ready, we’ll announce it on the podcast and through Patreon, so be sure to stay tuned for the official release.

Enter the Storz & Bickel VZ Giveaway:

https://forms.gle/gBLCEem9BwherVdYA

Connect With Dr. Miyabe Shields on LinkedIn:

https://www.linkedin.com/in/miyabeshields

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www.Patreon.com/Cannabichem

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