Gates Ag One-Technology Development for Smallholder Farmers in Africa and South Asia

Oncolytic viruses may offer a new way to tackle solid tumors by targeting cancer cells and activating the immune system. Dr. Eric Poma explains how Calidi Biotherapeutics is engineering a vaccinia-based virus to evade immune clearance, reach tumors, and deliver an immune-stimulating payload. He and Kevin Folta discuss the approach’s potential for cancers such as lung cancer, melanoma, renal cancer, and head and neck cancers.

This episode explores the fascinating history and science behind GLP1 receptor agonists, their development from animal venom to life-changing diabetes and obesity treatments, and the importance of basic research in medical breakthroughs.

In this episode, Dr. Alexia Groff discusses her groundbreaking research on expressing mammalian myoglobin in plants using chloroplast transformation. We explore the implications for food production, biosecurity, and future applications in meat substitutes and nutritional enhancement. Chloroplast inheritance reduces gene flow risk, enhancing biosafety. Heterologous expression in plants can produce functional animal proteins.

This episode explores the cutting-edge advancements in ALS diagnostics and treatment, highlighting how AI and digital health are transforming patient care and research. Guest Indo Navar shares her journey from Silicon Valley entrepreneurship to pioneering innovative solutions for ALS and other neurodegenerative diseases.

In this episode, Kevin Folta interviews Dr. Erik Ingelsson about innovative RNA-based therapies for obesity, focusing on the potential of silencing RNA and gene editing to target visceral fat and improve metabolic health.