Show Notes
Un nouvel épisode du Pharmascope est disponible! Dans ce 79ème épisode, Nicolas, Sébastien et Isabelle, inspirés par une populaire série documentaire, abordent l'utilisation des thérapies hormonales en ménopause. Les objectifs pour cet épisode sont: Expliquer le concept d'hormones bio-identiques Discuter des bénéfices et des risques associés à l'hormonothérapie en ménopause Conseiller adéquatement une patiente sur la prise d'hormones dans le traitement de la ménopause Pharmascope Medecine: (Protected Content)
Ressources pertinentes en lien avec l'épisode Série documentaire Loto-Méno Produit par KOTV, 2021. Disponible sur l'EXTRA d'ICI TOU.TV Revues systématiques portant sur l'efficacité et l'innocuité de l'hormonothérapie Maclennan AH et coll. Oral oestrogen and combined oestrogen/progestogen therapy versus placebo for hot flushes. Cochrane Database Syst Rev. 2004;2004:CD002978. Gaudard AMIS et coll. Bioidentical hormones for women with vasomotor symptoms. Cochrane Database Syst Rev. 2016;(8):CD010407. Rubinow DR et coll. Efficacy of estradiol in perimenopausal depression: so much promise and so few answers. Depress Anxiety. 2015;32:539-49. Lethaby A et coll. Hormone replacement therapy for cognitive function in postmenopausal women. Cochrane Database Syst Rev. 2008;2008:CD003122. Boardman HMP et coll. Hormone therapy for preventing cardiovascular disease in post-menopausal women. Cochrane Database Syst Rev. 2015;(3):CD002229. Marjoribanks J et coll. Long-term hormone therapy for perimenopausal and postmenopausal women. Cochrane Database Syst Rev. 2017;1:CD004143. Études WHI Rossouw JE et coll. Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results From the Women's Health Initiative randomized controlled trial. JAMA. 2002;288:321-33. Anderson GL et coll. Effects of conjugated equine estrogen in postmenopausal women with hysterectomy: the Women's Health Initiative randomized controlled trial. JAMA. 2004;291:1701-12. Manson JE et coll. Menopausal Hormone Therapy and Long-term All-Cause and Cause-Specific Mortality: The Women's Health Initiative Randomized Trials. JAMA. 2017;318:927-38. Étude WISDOM Vickers MR et coll. Main morbidities recorded in the women's international study of long duration oestrogen after menopause (WISDOM): a randomised controlled trial of hormone replacement therapy in postmenopausal women. BMJ. 2007;335:239. Autres références Hoibraaten E et coll. Increased risk of recurrent venous thromboembolism during hormone replacement therapy–results of the randomized, double-blind, placebo-controlled estrogen in venous thromboembolism trial (EVTET). Thromb Haemost. 2000;84:961-7. Rowe T. A Word About Bioidenticals. J Obstet Gynaecol Can. 2016;38:697-9. Plourde R, Tan R. L'hormonothérapie de remplacement. Quand, pour qui et comment? Le Médecin du Québec. 2020;55:41-6.
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