Show Notes
Link for free download of John's two text books, http://159.69.48.3/
Campbell's Pathophysiology Notes, Amazon orders for the UK, https://www.amazon.co.uk/dp/B012HWC8SU/ref=cm_sw_em_r_mt_dp_AYC5Q7G3H2B3T4BCHQY0 Campbell's Physiology Notes https://www.amazon.co.uk/dp/0955379725/ref=cm_sw_em_r_mt_dp_K0MXMAP26Y77TY4J90FB
Omicron, clinical picture (7th December)
Dr Angelique Coetzee, South African Medical Association
First to raise alarm about the new omicron
https://www.youtube.com/watch?v=BtELl7-zE_w
Totally different symptoms
Can be easily missed
Body aches and pains
Muscle pains
Headache
Tiredness (1 to 2 days)
Slight sore throat
No severe cough
No runny nose
Decrease in patients coming to doctors
South Africa vaccines
Pfizer
J and J
Hospitalizations, 99% unvaccinated
Symptoms more intense in unvaccinated
More intense but not severe
Body aches and pains
Muscle pains
Headache
Lateral flow testing and Omicron
Becomes positive after 24 hours up to 5 days
Very accurate
Omicron prevalence in SA
Ref for graphics (3rd December data)
SGTF has increased from 0.9% in October to 96.3% for November.
Children under the age of 12 years accounted for 7.9% of the SGTF positives,
and those 13 – 18 years old for 6.1%.
For week 47,
Hospital data from SA
Live data, hospital patients who have tested positive
Omicron and common cold
Omicron has insertion mutation ins214EPE
(From the common cold, HCoV-229E coronavirus)
Could have been acquired by switching
Involving the genomes of other viruses that infect the same host cells as SARS-CoV-2
It is plausible that the Omicron insertion could have evolved in a co-infected individual
PFIZER AND BIONTECH PROVIDE UPDATE ON OMICRON VARIANT
Preliminary laboratory studies demonstrate that three doses of the Pfizer-BioNTech COVID-19 Vaccine neutralize the Omicron variant (B.1.1.529 lineage),
while two doses show significantly reduced neutralization titers
Data indicate that a third dose of BNT162b2 increases the neutralizing antibody titers by 25-fold compared to two doses against the Omicron variant;
titers after the booster dose are comparable to titers observed after two doses against the wild-type virus which are associated with high levels of protection
As 80% of epitopes in the spike protein recognized by CD8+ T cells are not affected by the mutations in the Omicron variant, two doses may still induce protection against severe disease
The companies continue to advance the development of a variant-specific vaccine for Omicron and expect to have it available by March
in the event that an adaption is needed to further increase the level and duration of protection – with no change expected to the companies’ four billion dose capacity for 2022 Learn more about your ad choices. Visit megaphone.fm/adchoices
More from Dr. John Campbell
Dr. Clare Craig (doctor, pathologist, author, researcher). Excellent text on the pandemic, hard copy, Kindle and audio, https://www.amazon.co.uk/Expired-untold-Dr-Clare-Craig/dp/1739344707/ref=sr_1_1?crid=3E93FOWVOC0XX&dib=eyJ2IjoiMSJ9.JFeEViLIDz8rNi6E0HczPLFg-Rhhp0fkaEuFRtYftjRIDahju5qw8l9fofi8C2bD.CDOKUrBi_LzAdqysyTNwiaxvbEegCknK7-KFf6ouAdQ&dib_tag=se&keywords=expired+craig&qid=1758968302&sprefix=expired+craig%2Caps%2C129&sr=8-1
With Professor Robert Clancy Uploaded 29-03-25Learn more about your ad choices. Visit megaphone.fm/adchoices Learn more about your ad choices. Visit megaphone.fm/adchoices
Excess deaths by week, 2023Uploaded 05-04-21https://data-explorer.oecd.orghttps://stats.oecd.org/index.aspx?queryid=104676Australia, weeks 1 – 34, 202314,710 (16.8%)Covid deaths, 4,977Australia, 2022, weeks 1 - 5229,738 (18.7%)Australia, excess deaths 2022 + 2023 = 44,448Austria, week 1 – 44, 20234,444 (6.5%)Canada, weeks 1 – 33, 202328,400 (16.7%)Covid deaths, 4,613Canada, 202261,468 (22.3%)Canada, excess deaths 2022 + 2023 = 89,868Denmark, weeks 1 – 44, 20233,052 (6.9%)Covid deaths, 347Denmark, 20225,871 (11%)Denmark, excess deaths 2022 + 2023 = 8,923Finland, weeks 1 – 44, 20234,627 (10.5%)France, weeks 1 – 44, 202322,268 (4.9%)Covid deaths, 5,565France, 202271,751 (11.9%)Germany, weeks 1 – 44, 202359,039 (7.7%)Germany, 2022134, 578 (14.9%)Greece, weeks 1 – 44, 20235,132 (5.2%)Iceland, weeks 1 – 44, 2023209 (11.5%)Covid deaths, 0Iceland, 2022446 (20.2%)Israel, weeks 1 – 44, 20234,303 (11.8%)Covid deaths, 640Israel, 20227,050 (15.4%)Italy, weeks 1 – 44, 2023938 (0.28%)Netherlands, weeks 1 – 44, 202314,209 (11.3%)Netherlands, 202219,326 (13.2%)New Zealand, weeks, 1 – 44, 20233,960 (14.5%)New Zealand, 20225,787 (17.6%)Norway, weeks 1 – 44, 20231,885 (5.7%)Norway, 20224,980 (12.5%)Portugal, weeks 1 – 44, 20235,184 (6.3%)Spain, weeks 1 – 44, 202311,948 (3.7%)Switzerland, 1 – 44, 20232,063 (3.9%)UK, weeks 1 – 44, 202349,389 (9.44%)Covid deaths, 18,591UK, 202252,514 (9.26%)UK excess deaths 2022 + 2023 = 101,903Height of the Blitz, September 1940 to May 1941UK civilian deaths, 40,000Total civilian deaths for WW2, 70,000US, weeks 1 – 37, 2023155,763 (7.8%)Covid deaths, 76,187US, 2022495,749 (17.53)US excess deaths 2022 + 2023 = 651,512Total US deaths in Vietnam warThe U.S. National Archives shows that 58,220 U.S. soldiers perished.https://www.worldatlas.com/articles/how-many-americans-were-killed-in-the-vietnam-war.htmlHungary, weeks 1 – 44, 2023-3,785 (-3.2%)Poland, weeks 1 – 43, 2023104 (0.13%)Slovak republic, weeks 1 – 43, 2023-774 (-1.54%)Sweden, weeks 1 – 44, 2023-529 (0.6%)COVID, the untold story. So much more makes sense after this book and my first illuminating discussion with Dr. Craig. Get your copy in the UK here:https://www.amazon.co.uk/Expired-untold-Dr-Clare-Craig/dp/1739344707For friends in the US get your copy here, https://www.amazon.com/Expired-untold-Dr-Clare-Craig/dp/1739344707This dataset presents the latest data on All-cause death statistics Excess mortality and COVID-19 deaths, by week, for all OECD countries for which data are available.The expected number of deaths is based on the average number of deaths for the same week, (2015-19) This baseline could be considered a lower estimate of the expected number of deaths since both population growth and an ageing population would be expected to push up the number of deaths observed each year. For example, New Zealand saw its population grow by around 9% since 2015, with the number of people aged 65 and over increasing by 18%. Learn more about your ad choices. Visit megaphone.fm/adchoices Learn more about your ad choices. Visit megaphone.fm/adchoices
Millions of routine vaccinations missed because of covid disruptions.Uploaded 25-07-22COVID-19 pandemic and global childhood vaccinationshttps://www.who.int/news/item/15-07-2022-covid-19-pandemic-fuels-largest-continued-backslide-in-vaccinations-in-three-decadesCOVID-19 pandemic fuels largest continued backslide in vaccinations in three decadesGlobal vaccination coverage continued to decline in 2021, Data WHO and UNICEFDiphtheria, tetanus and pertussis (whooping cough) (DTP3)5% down between 2019 and 202125 million children missed out on one or more doses of DTP in 202118 million, zero dosesIndia, Nigeria, Indonesia, Ethiopia, Philippines, Myanmar, Mozambiquedevastating but preventable diseasesFactorsChildren living in conflict and fragile settingsIncreased misinformationCOVID-19 related issuesService and supply chain disruptionsResource diversionContainment measures, limited service accessCatherine Russell, UNICEF Executive DirectorThis is a red alert for child health. We are witnessing the largest sustained drop in childhood immunization in a generation. The consequences will be measured in livesWe need immunization catch-ups for the missing millions or we will inevitably witness more outbreaks, more sick children and greater pressure on already strained health systemsHuman papillomavirus (HPV) vaccineGlobal coverage of first dose of HPV vaccine, 15%A backdrop of rapidly rising rates of severe acute malnutritionWeakened immunity and missed vaccinationsa child survival crisis First dose measles coverageDropped to 81% in 202124.7 million children missed first measles dose5.3 million more than in 2019https://www.who.int/news/item/27-04-2022-unicef-and-who-warn-of--perfect-storm--of-conditions-for-measles-outbreaks--affecting-childrenJanuary and February 202217,338 measles casesJanuary and February 2021 9,665 measles cases2018140,000 measles deathsmostly among children under the age of fivehttps://www.who.int/news-room/fact-sheets/detail/measlesNZhttps://www.nzno.org.nz/resources/nursing_reports/pid/4779/ev/1/categoryid/25/categoryname/nursing-shortagesNinety-nine percent of responding members said the system was either in crisis (70%) or already beyond crisis (29%)End of Life Choice Act 2019 https://www.health.govt.nz/our-work/life-stages/assisted-dying-service/information-health-professionals/roles-delivery-service7 November 2021, terminal illness, meet specific criteria, ask for help to end life.https://www.legislation.govt.nz/act/public/2019/0067/latest/DLM7285905.htmlNFRsThe administration of assisted dying medication can only be done by a medical practitioner, or a nurse practitionerEuthanasia and assisted suicide Learn more about your ad choices. Visit megaphone.fm/adchoices Learn more about your ad choices. Visit megaphone.fm/adchoices
Important statement from Dr. Joseph Fraiman, physician and clinical scientist. Serious adverse events of special interest following mRNA COVID-19 vaccination in randomized trials in adults