NEJM This Week — October 22, 2026

This week, we feature new research on antithrombotic therapy after acute coronary syndrome, treatments for Sjögren’s disease and infective endocarditis, and a new therapy for small-cell lung cancer. We review advances in H. pylori infection, follow a case of vision loss, and report on innovations in hemophilia treatment, clinical research ethics, clinical trial prediction markets, payment models in primary care, Medicaid policy, and trust in medicine.