#Epi 86 - ICU Primary Snippet 29 - Renal Physiology - Urine concentrating mechanisms

In this episode, we discuss viscoelastic testing in ICU using ROTEM. We cover the main assays (EXTEM, INTEM, FIBTEM, APTEM and HEPTEM), the key parameters (CT, CFT, A10, MCF and ML), and the expected changes and underlying mechanisms in platelet dysfunction, therapeutic heparin use and hyperfibrinolysis. Read the full episode notes on Substack: https://critcareedu.substack.com/p/rotem-platelet-dysfunction-heparin

In this episode, we discuss the definition of morbid obesity and the cardiovascular changes associated with it, including effects on preload, left and right heart function, cardiac output, pulmonary and systemic circulation, coronary circulation, and cardiac conduction.

In this episode, we discuss the differences between EVD and intrapreanchymal ICP monotors.

In this episode, we discuss the pharmacology of Meropenem.