Show Notes
*** All content and media by Project 100 is created and published online for informational purposes only. It is not intended to be a substitute for professional medical advice and should not be relied on as health or personal advice. *** In Part 2 of my discussion with neuroscientist Dr Sarah McKay, we kick off by looking at the prevalence of dementia—particularly Alzheimer’s—in Australia, and why women are disproportionately affected. We also dive into the physiological shifts that occur during perimenopause—specifically the hormonal fluctuations that can affect brain function, sleep, and emotional stability. Dr McKay shares what the latest science says about Hormone Replacement Therapy (HRT): where it helps, where it doesn’t, and how it fits into the broader picture of women’s brain health. One product I’ve recently added to my routine from the Bulk Nutrients range is their NMN Extend. It’s a science-backed blend of 10 powerful ingredients, including NMN, Resveratrol, and Hyaluronic Acid, designed to support everything from energy and muscle recovery, to skin hydration, joint health, and event mental clarity. Check out their NMN extend product here: https://www.bulknutrients.com.au/products/nmn-capsules Eight Sleep’s newest generation, Pod 5. isn’t just another bed-frame add-on; it’s a high-tech mattress cover that actively adjusts to your body temperature throughout the night, cooling, warming, and even elevating your body when needed, all based on real-time data. The new Pod 5 introduces for the first time, a hydro-powered blanket system, utilising the same technology as the cover to extend temperature regulation across your entire body, not just the mattress surface. Clinically proven to increase quality sleep by up to one hour each night, it’s basically like having an AI-powered sleep coach, personal thermostat, and advanced health tracker working for you while you rest. Head on over to eightsleep.com/project100 and use the code PROJECT100 (that’s Project one-zero-zero) and get up to $550 off your very own Pod 5. Trust me, your body will thank you for this investment in better sleep. The all-new WHOOP is here — now 7% smaller with 14+ days of battery life. New features like Healthspan show how your daily habits are affecting your rate of aging — and now you can check your blood pressure straight from your wrist. If you’re serious about performance, longevity, and actual progress — this is it. Sign up for a one-month free trial at WHOOP.com — or visit join.whoop.com/mentored for one month off your annual membership fee.
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More from Project 100 with Mark Bouris
All content and media by Project 100 is created and published online for informational purposes only. It is not intended to be a substitute for professional medical advice and should not be relied on as health or personal advice. **** Sleep is the cheapest longevity tool on the planet — and most of us are doing it wrong. Dr jemma King, sleep researcher and author of *Sleep Smarter, Think Sharper, Feel Better*, breaks down the science of what actually happens when you close your eyes: from the human growth hormone spike that only hits in your first two sleep cycles, to why your late-night coffee is still in your bloodstream at 2 AM. This is one of those conversations that will change how you think about every single night. Practical, science-backed, and no fluff. See omnystudio.com/listener for privacy information.
All content and media by Project 100 is created and published online for informational purposes only. It is not intended to be a substitute for professional medical advice and should not be relied on as health or personal advice. ****
Most Australians know alcohol isn't great for them — but almost nobody knows it directly causes 7 types of cancer, or that just 3 standard drinks a week raises breast cancer risk by 15%. Dr Chris Davis is a GP and addiction specialist who built a telehealth program to make alcohol treatment actually accessible — no waiting lists, no rehab wards, no judgment. In this episode we get into the chemistry of what alcohol actually does to your body, why your sleep is being quietly destroyed, and what the data says about who's really drinking at risky levels in this country. If you drink — or love someone who does — this one's worth your time.
All content and media by Project 100 is created and published online for informational purposes only. It is not intended to be a substitute for professional medical advice and should not be relied on as health or personal advice. **** Lucas Aoun is a naturopath and men's health researcher with a Bachelor of Health Science whose work on natural testosterone optimisation gained the attention of Andrew Huberman. In this episode, he walks through the full hormone production pathway from the hypothalamus to the testes, explains which blood markers most GPs overlook, and outlines the lifestyle, nutrition, and supplementation strategies he has used to bring his own testosterone to near-1,000 nanograms per deciliter naturally. The conversation also covers structural causes of low testosterone, the role of HBOT and sleep in hormone health, and when TRT becomes the appropriate next step. Check out Lucas's stack here: https://www.inb4supps.com/products/peak-t See omnystudio.com/listener for privacy information.
Most people think longevity is about diet and supplements. Alexis Fernandez, cognitive neuroscientist, says the real killers are chronic stress, isolation, and outsourcing your brain to your phone. In this episode of Project 100, Mark Bouris sits down with Alexis to unpack what the science on centenarians actually shows — and it's simpler, and more confronting, than most people want to hear. From cortisol dysregulation to synaptic pruning to why resistance training is the best thing you can do for your brain, this conversation will change how you think about what it means to age well. See omnystudio.com/listener for privacy information.