Show Notes
Alex Kikel is a clinician focused on advanced hormone optimisation, mitochondrial health, and neurochemical balance. In this episode, we unpack what it really takes to upgrade the human system at every level. We get into why most people approach optimisation backwards, chasing surface-level tools without building foundational capacity first. Alex breaks down how to layer protocols based on biological priorities: starting with circadian rhythm, blood sugar control, and mineral status, before moving into peptides, thyroid support, and androgen management. We also cover the smart use of methylene blue, the dangers of overusing NAD+, and how to interpret biofeedback in real time.
Timestamps: 01:00 Starting with mitochondria and how to feel 25 again 04:01 Grounding, sunlight and building up mitochondrial potential 06:23 Macronutrients, fasting, and feasting for brain energy 11:32 Fuelling flexibility with ketones, glucose, oxygen, and choline 14:45 Entry-level supplements for cognitive clarity 16:52 Basic vs advanced stack: B vitamins to plasmalogens 19:10 Methylene blue, brain overdrive, and proper dosing 22:53 SLU-PP-332 and the rise of mitochondrial peptides 26:14 Understanding MOTS-c and mitochondrial-driven fat loss 29:36 Best injectable protocols for cognitive slumps 33:21 Measuring peptide efficacy with inflammation markers 35:27 NAD+, precursors, detox blockers and delivery methods 39:10 Testosterone support via peptides, supplements, and bioregulators 44:41 Growth hormone: ipamorelin, tesamorelin, exogenous GH 49:20 IGF-1 timing and stacking it post-workout for gains 56:00 Splitting GH and tesamorelin for fat loss and performance 59:51 Optimal daily protocol: from sunrise to sleep 1:06:20 Recovery day protocol with grounding and anti-inflammatory tools 1:10:19 Healing peptides: BPC-157, TB-500 and systemic benefits 1:14:43 GLP-1s explained: semaglutide to Retatrutide and future therapies 1:20:54 Emerging 5-stage agonists and injectable mitochondria
DISCLAIMER Nothing shared on this podcast is a substitute for professional medical guidance. Please consult a healthcare professional before making any health or lifestyle changes. Hack You Media Instagram: https://www.instagram.com/hackyoumedia/ TikTok: https://www.tiktok.com/@hack.you.media?lang=en More: https://hackyou.media/#aa19104a-abc1-4697-b0f5-0e81e47e60c5 Follow Vadim Instagram: https://www.instagram.com/vadim_bioniq/?hl=en Bioniq: https://www.bioniq.com/ Follow Alex Instagram: https://www.instagram.com/alex_kikel/?hl=en Website: https://theprepcoach.com/
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