The Precision-Guided Podcast

Episode 71: US-Mexico Relations in the Shadow of Fentanyl with Dr. Vanda Felbab-Brown Part 1

The Precision-Guided Podcast

Show Notes

Amid President-elect Donald Trump’s recent pledge to impose a 25% tariff on Mexican products, if Mexico does not curb the flow of fentanyl, this episode dives deep into the complexities of U.S.-Mexico relations and the fight against organized crime. Join host Nelly Hernandez Valdez and policy expert Dr. Vanda Felbab-Brown as they explore: Fentanyl and the Cartels: How Mexican criminal groups have become key players in the U.S. fentanyl epidemic and their strategies for controlling local economies and territories.

China's Role: The connection between Chinese criminal groups and Mexico’s illegal economies and its implications for global security.

Bi-national Cooperation: Why has the Bicentennial Framework between the Biden and Lopez Obrador administrations seen limited progress, and what can we expect under President Claudia Sheinbaum and President-elect Donald Trump as they inherit this complex relationship.

Weapons Trafficking: The U.S. gun industry’s impact on cartel firepower and whether reforming firearm policies could disrupt organized crime.

Policy Proposals: The effectiveness of proposed measures, such as designating cartels as foreign terrorist organizations or employing military force, and what policymakers can do to achieve real results.

Dr. Vanda Felbab-Brown is a senior fellow in the Strobe Talbott Center for Security, Strategy, and Technology in the Foreign Policy program at Brookings. She is the director of the Initiative on Nonstate Armed Actors and of the Brookings series "The Fentanyl Crisis in North America and the Global Reach of Synthetic Opioids. She is also the co-director of the Africa Security Initiative. Previously, she was the co-director of the Brookings projects “The Opioid Crisis in America: Domestic and International Dimension," “Improving Global Drug Policy: Comparative Perspectives Beyond UNGASS 2016,” and “Reconstituting Local Orders.” Dr. Felbab-Brown is an expert on international and internal conflicts and nontraditional security threats, including insurgency, terrorism, organized crime, urban violence, and illicit economies. Her fieldwork and research have covered, among others, Afghanistan, South Asia, Burma, Indonesia, the Andean region, Mexico, Iraq and other parts of the Middle East, and various parts of Africa. She was a senior advisor to the congressionally-mandated Afghanistan Peace Process Study Group. A frequent commentator in international and U.S. media, Dr. Felbab-Brown regularly provides testimonies to the U.S. Congress. She also hosts the podcast show “The Killing Drugs: Synthetic Opioids Around the World. ”

More from The Precision-Guided Podcast

Mar 17, 2026

The aftermath of the Russian invasion of Ukraine has seen a resurgence of interest in the topic of transatlantic security. Discussions of why the war in Ukraine began often focus on debates over the wisdom of NATO expansion in the post-Cold War era; the rise of a revisionist, increasingly imperialist Russia under Putin; and the escalating security dilemma entailed by these two dynamics. While these factors are certainly important in explaining how the Russian full-scale invasion of Ukraine came about, the story of how U.S. and NATO-Russia relations evolved in the post-Cold War period is one with considerably more nuance than is often represented in contemporary geopolitical commentary. To try and enhance the depth of public discourse on this critical subject, Dr. Stephen Flanagan joins host Mark McGuire on this episode of the Precision Guided Podcast to offer his insights on the evolution of US/NATO-Russia relations in the post-Cold War era.

Oct 17, 2025

Arun Gupta, CEO of NobleReach, discusses the importance of combining industry and government to foster innovation in the national security and technology landscape. The relationship between public and private sector talent is based on trust and provides a unique opportunity to make advancements. Additionally, this period in innovation marks an unprecedented shift from historical government-led innovation to private sector-led development. Furthermore, Russia’s War against Ukraine demonstrates this relationship between the government and private sector while pursuing innovation and national security. Arun leaves listeners with three recommendations for how individuals can contribute to the technology and innovation needed to improve national security.

Jul 26, 2025

This episode dives into the rapidly evolving landscape of artificial intelligence (AI) and explores how recent trends and developments in the technology continue to transform. This episode also examines the growing challenges of content moderation, as many social media companies continue to scale back their moderation efforts. Peyton Taylor (SSP‘25) hosts Dr. Daniel Byman, Director of the Security Studies Program at Georgetown University and Director of the Warfare, Irregular Threats, and Terrorism Program at CSIS.

Jul 1, 2025

Sea control is more important than ever. With 80-90 percent of the global trade over sea, it is impossible to maintain the current economic order without stability and security of the world's major trading routes. However, more forces than ever are able to destabilize the global maritime network. Whether it is a resurgence in piracy, increased terrorist threats, or state paramilitary organizations, the number of threats at sea is increasing. Today we sat down with Pieter Zhao to discuss these new threats. We also talk about his research into how states are choosing to meet these threats including his work on private maritime security firms and paramilitary maritime forces. Articles Discussed: https://digital-commons.usnwc.edu/nwc-review/vol77/iss1/7/ https://militairespectator.nl/artikelen/winning-without-fighting-indo-pacific

Apr 13, 2025

Amid President-elect Donald Trump’s recent pledge to impose a 25% tariff on Mexican products, if Mexico does not curb the flow of fentanyl, this episode dives deep into the complexities of U.S.-Mexico relations and the fight against organized crime. Join host Nelly Hernandez Valdez and policy expert Dr. Vanda Felbab-Brown as they explore: Fentanyl and the Cartels: How Mexican criminal groups have become key players in the U.S. fentanyl epidemic and their strategies for controlling local economies and territories.

See all episodes →