Show Notes
Can neuroscience explain what happens to the brain on psychedelics? And even if we map the brain while it’s tripping, does that tell us why these experiences can be so transformative? We’ll talk with some of the pioneers in psychedelic research — from Amanda Feilding’s boundary-busting work to Robin Carhart-Harris’ theory of the "entropic brain." Also, renowned neuroscientist Christof Koch goes down the rabbit hole on 5-MeO-DMT, also known as toad venom. — 00:00:00 Introduction 00:02:25 Christof Koch on Toad Venom 00:24:00 Amanda Feilding's Beckley Foundation 00:32:20 David Nutt on Drug Policy 00:40:00 Robin Carhart-Harris and Entropy —
Bio: Christof Koch
Bio: Amanda Feilding
Bio: David Nutt
Bio: Robin Carhart-Harris
Bio: Gül Dölen
WPR: "Exploring consciousness on toad venom"
WPR: "The godmother of the European psychedelic revival"
WPR: "How therapeutic psilocybin could help heal long-buried trauma"
WPR: "Magic mushrooms and the 'entropic brain'"
This episode also aired as an episode of "To The Best Of Our Knowledge" on Wisconsin Public Radio
More from Luminous: A Podcast about the Science, Philosophy and Culture of Psychedelics
We all know Timothy Leary, the high priest of ‘60s psychedelia, but his partner, Rosemary Woodruff Leary, has largely been forgotten. She also had a remarkable life, even breaking Leary out of prison with the help of the Weather Underground. Now, biographer Susannah Cahalan tells her story — from the heady Sixties to a life on the run for decades. — 00:00:00 Introduction 00:05:40 Before Timothy Leary 00:10:40 Millbrook 00:20:00 Prison Break and Exile 00:36:00 Twenty Years as an Innkeeper —
Thomas Metzinger is a renowned German philosopher. He has a longtime fascination with psychedelics, stemming from his own experience and also from his work as an analytic philosopher. He says altered states of consciousness give us profound insights into the nature of the mind. And he believes modern society has an ethical imperative to foster a “culture of consciousness.” — 00:00:00 Introduction 00:03:10 Is There Knowledge in These States 00:06:55 Metzinger's Own Experiences 00:19:45 When It Backfires 00:28:15 A Concrete Proposal — Bio: Thomas Metzinger
Most psychedelic stories are highly personal, but there’s a different dynamic when two people share the experience — especially a married couple. Steve talks with theoretical physicist Marcelo Gleiser and clinical psychologist Kari Gleiser about their transformative experiences. — 00:00:00 Introduction 00:08:45 A Physicist's First Journey 00:17:30 Reattaching Mind and Body 00:26:15 Kari's Clinical Practice 00:44:00 What a Shared Trip Opens Up —
Chris Timmerman is a neuroscientist with a deep interest in phenomenology—what’s actually happening in our minds during psychedelic experiences. He leads the DMT Research Group at Imperial College, where he’s found that a single psychedelic experience can transform a person’s belief system, often turning materialists into panpsychists. In this wide-ranging conversation, Steve talks with Chris about everything from fractals and ayahuasca ceremonies to whether scientists who study psychedelics should talk openly about their own experiences. — 00:00:00 Introduction 00:06:40 Why Study Non-Ordinary States 00:16:05 What DMT Does to the Brain 00:29:15 Entities and Scientific Caution 00:49:40 The Questions Still Open — Bio: Chris Timmermann
Buddhist meditation and psychedelic journeys have a lot of shared DNA—both take you deep inside your mind and can change your life. But many Buddhists say psychedelics violate the prohibition against intoxicants. Do they? Spring Washam straddles this divide as both a Buddhist teacher and founder of an ayahuasca church. Her own story is fascinating—how she’s merged these two practices. — 00:00:00 Introduction 00:03:30 Finding Buddhism in Oakland 00:12:55 When the Boat Cracked 00:25:10 Two Traditions, Both True 00:42:05 A Church in Georgia — Bio: Spring Washam