Show Notes
What makes TAVI in bicuspid aortic valve disease so challenging—and how can those challenges be overcome? In this #europcr 2025 expert discussion, Chiara De Biase, Kentaro Hayashida, and Didier Tchetche share practical insights on navigating anatomical variability, refining patient selection, and optimising valve sizing. They also address the critical role of calcification and how it can influence procedural outcomes. Whether you're performing TAVI in complex cases or building your expertise, this conversation offers valuable takeaways you won’t want to miss! Hosted on Acast. See acast.com/privacy for more information.
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In this #europcr 2026 conversation, Andreas Baumbach speaks with Raj Makkar about one of the most rapidly evolving areas in structural heart interventions: TAVI for aortic regurgitation. While TAVI has become an established treatment for aortic stenosis, managing patients with pure native aortic regurgitation remains more challenging. In recent years, dedicated transcatheter devices have been developed and evaluated, with encouraging results in patients who are at high surgical risk or unsuitable for surgery. The discussion focuses on the ALIGN-AR study, which assessed a dedicated TAVI device in patients with symptomatic, moderate-to-severe or severe aortic regurgitation who were not appropriate candidates for surgery. Andreas Baumbach and Raj Makkar review the study design, patient population, and key outcomes, and discuss how these findings may influence clinical practice. They also explore the current guideline recommendations and the future role of transcatheter therapies in the management of aortic regurgitation. Listen to this insightful discussion to learn about the latest evidence and emerging treatment options for this challenging patient population. Hosted on Acast. See acast.com/privacy for more information.
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Julien Dreyfus and Fabien Praz review the current indications and management of severe tricuspid regurgitation, highlighting that treatment is now recommended for symptomatic patients, and emphasising the importance of early referral before irreversible organ damage occurs. They outline a stepwise, multimodality diagnostic approach performed in expert heart valve centres, combining echocardiography, CT, right heart catheterisation and heart team evaluation to guide decision-making. Recent evidence shows that effective reduction of tricuspid regurgitation, whether through repair or replacement, can improve symptoms and reduce heart failure hospitalisations. The key message is that timely diagnosis, appropriate patient selection, and a tailored strategy are essential to optimise outcomes. Hosted on Acast. See acast.com/privacy for more information.
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