Stop Disease 5 Years Early: AI + DNA Playbook With 23andMe's Founder Anne Wojcicki

James Manyika runs research and labs at Google, and his team recently studied millions of real Gemini conversations to see how people use AI at work. In a typical job, it's only about a fifth of the tasks. I asked him what that means for your job and your salary, why he bet against the people who predicted half of white-collar jobs would disappear in two years, which three signals would change his forecast, and which AI breakthroughs are already in your life without you noticing.📩 Follow my Newsletter: https://siliconvalleygirl.beehiiv.com/subscribe?utm_source=spotify&utm_medium=description&utm_campaign=futureproof-sub&utm_content=30-days-plan&utm_term=james-manyika

Brian Chesky built Airbnb into an S&P 500 company, and he says starting a business today is easier than it was 20 years ago. In this episode we go step by step: how Airbnb is becoming AI-native, why chat is the wrong interface for most work, how Brian generates 30,000 ideas a year and picks the ones worth doing, why the phone is the enemy of focus, and the one habit that separates real builders from everyone else. 📩 7 skills that make you irreplaceable: https://siliconvalleygirl.beehiiv.com/p/7-skills-that-make-you-irreplaceable-adc6?utm_source=spotify&utm_medium=description&utm_campaign=futureproof-sub&utm_content=7-Brian-Chesky

Daron Acemoglu is an MIT economist and a 2024 Nobel laureate in Economic Sciences. He believes some of AI’s biggest business opportunities are being overlooked—but where does he see the real money, and what should you learn to stay valuable?

Greg Brockman co-founded OpenAI and previously served as CTO of Stripe. He believes AI could spark a massive renaissance of entrepreneurship—but what should we actually build when the models keep getting better? In this episode, I show Greg the AI app I created to prepare for our interview and ask how to make it more ambitious. We talk about what makes an AI product worth paying for, why domain expertise matters more than ever, and how founders and small-business owners can use AI today.

The U.S. Bureau of Labor Statistics projects which jobs will grow through 2035, and it rated 831 occupations by how much of the work AI can do or help with. I went through the data to find the careers where demand is growing, what they pay, and what it takes to get in.We rank 10 growing careers by median salary, from management analysts at $101,860 to computer and information systems managers at $175,140. You'll see why nurse practitioners are the fastest-growing occupation in the country, why software developers are still projected to add 174,700 jobs, and which six-figure healthcare job sits in the lowest AI exposure group. Then we look at the five occupations shrinking fastest and what they have in common.At the end, I show you a simple exercise from Stanford economist Erik Brynjolfsson. Split your last two weeks of work into define, execute and evaluate. Pick one repetitive task, try it with AI, and check the result. Then decide what responsibility you want to grow into with the time you get back.📌 FREE: my 20-minute AI agent setup — no code needed. Subscribe to Future Proof for the free guide →https://siliconvalleygirl.beehiiv.com/p/your-first-autonomous-agent-in-20-min-5429?utm_source=spotify&utm_medium=video&utm_campaign=futureproof-sub&utm_content=first-agent&utm_term=10professions 🎧 *Full conversation with Erik Brynjolfsson:* https://open.spotify.com/episode/3lyMQ1Qg7ybNJIgAmAzq97?si=8JYKTMIxS_aKYidy2AfcZw