Clinical Misfits: Why Are Neurodivergence, Dysautonomia and hEDS So Connected?

Clinical Misfits returns for Season Two with a deeper, more conversational approach to the connections between neurodivergence and complex chronic illness.

In this episode, Dr Mary revisits ideas explored in Season One before turning her attention to hypermobile Ehlers-Danlos syndrome (hEDS), dysautonomia and their relationship with neurodivergence. She explores the potential role of chondroitin sulfate in connective tissue and the nervous system, including its involvement in structures surrounding nerve cells known as perineuronal nets.

From there, Dr Mary considers how differences in synaptic pruning could influence the way neurodivergent nervous systems process and retain signals. Using pain and the body's autonomic response as an example, she explores a possible connection between neurological development, heightened nervous-system responses and the complex physical symptoms experienced by many neurodivergent people.

Produced for the Autistic Culture Podcast Network.

🎧 Clinical Misfits is available on Spotify, Apple Podcasts, and all major platforms. 🌈 Celebrate autistic voices with early access, ad-free listening, and our full archive at AutisticCulturePlus.com 🌐 Visit www.autisticculturepodcastnetwork.com 📲 Follow us on Instagram: @autisticculturepodcast 🎙️ Executive Producers: Amy Burns, Anamaria B Call, Andrew Banner, Anna Goodson, Ashley Apelzin, Audrea Volker, Ben Coulson, Brian Churcek, Cappy Hamper, Carley Biblin, Charlene Deva, Chloe Cross, Clay Duhigg, Clayton Oliver, Danny Dunn, Daria Brown, David Garrido, Emily Burgess, Eric Crane, Erik Stenerud, Fiona Baker, Grace Norman, Helen Shaddock, Jaimie Collins, Jason Killian, Jen Unruh, Jennifer Carpenter, Julia Tretter, Kathie Watson-Gray, Kenneth Knowles, Kira Cotter, Kristine Lang, Kyle Raney, Llew P Williams, Laura Alvarado, Laura De Vito, Laura Provonsha, Lily George, Nelly Darmi, Nigel Rogers, Rachel Miller, Tim Scott, Tyler Kunz, Victoria Steed, Yanina Wood.

🎧 Producers: AJ Knight, Bobby Simon, Da Kovac, Eleanor Collins, Emily Griffiths, Hannah Hughes, Jennifer Kemp, Jonas Fløde, Kate F, Katie N Benitez, Kendra Murphy, Lisa Dennys, Logan Wall, Louise Lomas, Melissa Nance, Nicola Owen, Rebecka Johansson, Sam Morris, Sarah Hannah Morris. Hosted on Acast. See acast.com/privacy for more information.