Mitochondrial medicine: The biophysics prescription with Lisa Costa-Bir and Dr Christabelle Yeoh
FX Medicine Podcast CentralShow Notes
Dr Christabelle Yeoh, integrative medicine physician, joins Lisa Costa-Bir for a deep dive into mitochondria — the organelles influencing nearly every tissue and process in the body. Moving beyond the outdated “powerhouse of the cell” view, Dr Yeoh explains how mitochondria act as processors of energy and evolutionary sentinels of immunity, redox balance, and cellular plasticity.
This episode explores how dysfunction manifests clinically — from fatigue and brain fog to autonomic dysregulation, poor vitamin D supplementation uptake, and maternal-line inheritance patterns. Dr Yeoh also shares practical “biophysics prescriptions”: exposure to sunrise and sunset, blocking blue light, eating only in daylight hours, grounding in nature, and regular movement to support mitochondrial quality control.
Warm, engaging, and invested in her subject, Dr Yeoh empowers practitioners with insights that place mitochondrial health as the foundation for patient care — and shows why aligning with natural rhythms is essential for resilience and recovery.
Covered in this episode:
(01:02) Welcome Dr Christabelle Yeoh
(03:36) What are the mitochondria?
(08:38) ATP and inflammation
(12:42) Mitochondria manipulating us?
(15:21) Mitohormesis
(17:22) Stress
(22:46) Mitochondrial dysfunction
(28:25) Timeline for mitochondrial change
(32:18) Blood testing
(36:05) Zeitgebers
(41:21) Psychological stress
(44:08) Biophysics prescription
(48:52) Latest research
(50:28) Final remarks
Find today's transcript and show notes here: https://www.bioceuticals.com.au/education/podcasts/mitochondrial-medicine-the-biophysics-prescription
Sign up for our monthly newsletter for the latest exclusive clinical tools, articles, and infographics: www.bioceuticals.com.au/signup/
DISCLAIMER: The information provided on fx Medicine is for educational and informational purposes only. The information provided is not, nor is it intended to be, a substitute for professional advice or care. Please seek the advice of a qualified health care professional in the event something you learn here raises questions or concerns regarding your health.
More from FX Medicine Podcast Central
In this podcast episode, Emma Sutherland speaks with Dr Nick Fuller, Clinical Trials Director at the Royal Prince Alfred Hospital Endocrinology Department and researcher at the Charles Perkins Centre. Together they unpack the complex physiology behind weight regain, including metabolic adaptation, appetite-hormone shifts, and the evolutionary mechanisms that make long-term weight loss so challenging.
Dr Stacy Sims, expert in female physiology and training, collaborates with fx Ambassador Lisa Costa-Bir to discuss the intricate relationship between hormones and physical performance.
Jane Hutchens, naturopath and reproductive health and human genetics expert, along with fx Medicine ambassador, Emma Sutherland, raise awareness on the importance of understanding cardiovascular health implications during pregnancy and post-partum. This impacts 1 to 4 percent of women in Australia and is under recognized and underreported.
In part two of our Perspectives podcast, fx Medicine by BioCeuticals ambassadors Lisa Costa-Bir, Dr Michelle Woolhouse, Mick Alexander and Dr Adrian Lopresti, join host Emma Sutherland to explore practical, evidence-aligned treatment strategies for patients with cardiometabolic dysfunction. The discussion covers GLP-1 receptor agonists (GLP-1 RAs) including side effect management and dietary and lifestyle support. They also discuss the evolving landscape of new cardiometabolic medications, and the behavioural, psychological, and social factors that shape long-term cardiometabolic outcomes.
In this insightful conversation, naturopathic doctor and bestselling author Lara Briden joins Emma Sutherland to explore androgen physiology, excess, and sensitivity in women. Together they discuss the complexities of diagnosing androgen excess, including polycystic ovarian syndrome (PCOS) and adrenal-driven cases, and examine the metabolic consequences of chronically elevated androgens. They discuss the challenging clinical presentation of female pattern hair loss or androgenic hair loss talking about cause and realistic treatments.