EB. 138: How Low-Carb Diets Worsen AGE Formation (and What to Do Instead)
The Energy Balance PodcastShow Notes
In this episode we discuss:
How glucose and insulin decrease glycation
Why ketogenic diets can be worse than high-carb diets when it comes to AGE formation
How autophagy helps to clear AGEs, but increasing autophagy is not the answer
The true primary drivers of AGE accumulation
The best diet and supplements for minimizing glycation
Check out the Energy Balance Mini-Course here: https://www.jayfeldmanwellness.com/energy/ Check out the Energy Balance Food guide here: https://www.jayfeldmanwellness.com/guide/ Check out the Energy Balance Solution here: https://www.jayfeldmanwellness.com/energy-balance-solution/
Click here to check out the show notes: https://www.jayfeldmanwellness.com/eb-138-low-carb-diets-increase-glycation-and-what-to-do-instead/
Timestamps: 0:00 – intro 0:57 – how glycation products are detoxified and cleared from the body 4:03 – glycation detoxification is impaired by oxidative stress and inflammation, as seen in type 2 diabetes 7:56 – the benefits of carbohydrates for the detoxification of glycation products 10:42 – the benefits of insulin for the detoxification of glycation products 12:45 – how AGEs are cleared 14:36 – increasing autophagy via hormesis is not the answer for clearing AGEs 19:09 – autophagy can drive disease 20:50 – ATP protects against oxidative stress and allows for proper autophagy when needed 24:37 – impaired mitochondrial along with fatty acid oxidation impairs autophagy and increases oxidative stress 26:54 – carbohydrates do NOT inhibit autophagy 29:18 – adequate thyroid hormone supports proper autophagy 30:15 – adequate ATP and mitochondrial function is needed for the UPS (ubiquitin proteasome system) 32:56 – do high-carb diets actually impair metabolism and insulin sensitivity 35:26 – is fructose really worse for blood sugar regulation and glycation? 37:16 – are low-carb or ketogenic diets the solution to reduce glycation? 40:32 – increased glycation and oxidative stress on ketogenic diets 44:09 –low-carb diets don’t prevent glucose exposure 47:56 – there are still considerable insulin and glucose excursions on low-carb diets 50:06 – gluconeogenesis leads to same glycolytic intermediates as glucose metabolism 51:52 –the main driver of AGE formation and impaired AGE clearance 53:40 – the role of vitamin B1 (thiamine) and mitochondrial energy production in decreasing AGEs 56:27 –endotoxin as a driver of glycation and increased AGE production 58:12 – hypothyroidism as a driver of glycation and AGE accumulation 59:37 – dietary solutions for reducing glycation and AGEs 1:03:33 – how to support the glyoxalase pathway to support the detoxification of glycation products 1:05:56 – avoid calorie restriction, low-carb diets, fasting, resveratrol, cold exposure, excess exercise, and iron overload to decrease glycation and AGEs 1:07:33 – iron as a double-edged sword for oxidative stress
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Check out the Energy Balance Food guide here: https://www.jayfeldmanwellness.com/guide/ Check out the Energy Balance Mini-Course here: https://www.jayfeldmanwellness.com/energy/ Check out the Energy Balance Solution here: https://www.jayfeldmanwellness.com/energy-balance-solution/ Show Notes: https://www.jayfeldmanwellness.com/the-cancer-doctor-is-wrong-about-cancer/
Check out the Energy Balance Mini-Course here: https://www.jayfeldmanwellness.com/energy/ Check out the Energy Balance Food guide here: https://www.jayfeldmanwellness.com/guide/ Check out the Energy Balance Solution here: https://www.jayfeldmanwellness.com/energy-balance-solution/ Show Notes: https://www.jayfeldmanwellness.com/the-cancer-doctor-is-wrong-about-cancer/
Free Energy Balance Food Guide: https://jayfeldmanwellness.com/guide The Nutrition Blueprint: https://mikefave.com/the-nutrition-blueprint/ Theresa's Instagram: https://www.instagram.com/theresapiela Timestamps: 0:00 – intro 2:17 – Anthony Jay suggests that sugar is a worse fuel than fat 11:33 – is insulin resistance the cause of arterial plaque and heart disease? 16:47 – does the heart become “addicted” to sugar in insulin resistance and cardiovascular disease? 24:38 – fat metabolism is worse for insulin resistance in the heart 34:25 – don’t feed babies sugar or carbohydrates? do carbs drive heart disease? 44:55 – what Anthony Jay gets wrong about statins and diabetes 52:17 – after years of low-carb, she reversed fatigue, brain fog, and hormonal problems using a bioenergetic approach
Free Energy Balance Food Guide: https://jayfeldmanwellness.com/guide The Nutrition Blueprint: https://mikefave.com/the-nutrition-blueprint/ Theresa's Instagram: https://www.instagram.com/theresapiela Timestamps: 0:00 – intro 1:55 – what Layne Norton eats in a day: protein bars, microwave meals, cereal, protein shakes 5:54 – problems with the “if it fits your macros” (IIFYM) diet camp 11:54 – the glaring hypocrisy in Layne Norton’s “no influencer BS” diet 17:43 – what Layne Norton eats in a day cont’d: frozen meals, popcorn, frozen yogurt, chicken + apples 20:12 – “consistency over perfection” mindset: terrible advice? 25:44 – “normal” may not be “healthy” 28:25 – is it possible to prioritize health on a busy schedule? 34:13 – time saving tips for healthy meal prep 42:47 – is Layne Norton’s diet any better than fast-food? 47:01 – social media vs reality: how health influencers hide their health issues 50:56 – success story: cravings eliminated by adding carbs post carnivore
Free Energy Balance Food Guide: https://jayfeldmanwellness.com/guide The Nutrition Blueprint: https://mikefave.com/the-nutrition-blueprint/ Theresa's Instagram: https://www.instagram.com/theresapiela Timestamps: 0:00 – intro 2:12 –Thomas Delauer admits that intermittent fasting increases cortisol 9:38 – what fasting does to your digestion, thyroid, hormones, and metabolism 15:40 – why intermittent fasting is stressful and increases cortisol 20:20 – Thomas Delauer says intermittent fasting every day is harmful 28:06 – the consequences of long-term intermittent fasting 32:09 – more fat-burning doesn’t mean better health 35:34 – Thomas DeLauer’s new approach to fasting: does it actually make sense? 41:29 – should we try to increase autophagy for better health? 45:56 – are longer fasts better than daily intermittent fasting? do they improve insulin sensitivity? 53:13 – the best way to increase autophagy 1:04:30 – what to do if fasting makes you feel better 1:15:03 – restoring health and finding balance after vegan, OMAD, and carnivore diets