Dr. John Campbell

International omicron multiplication

Dr. John Campbell

Show Notes

Link for free download of John's two text books, http://159.69.48.3/

Campbell's Pathophysiology Notes, Amazon orders for the UK, https://www.amazon.co.uk/dp/B012HWC8SU/ref=cm_sw_em_r_mt_dp_AYC5Q7G3H2B3T4BCHQY0 Campbell's Physiology Notes https://www.amazon.co.uk/dp/0955379725/ref=cm_sw_em_r_mt_dp_K0MXMAP26Y77TY4J90FB the disease is mild in almost all of the cases seen so far,

Dr Rochelle Walensky, CDC

https://www.theguardian.com/world/2021/dec/09/cdc-chief-omicron-mild-early-data-us-spread-variant

75% of US cases vaccinated

Scotland, 'tsunami' of Omicron

https://www.dailymail.co.uk/news/article-10295867/Omicron-infecting-4-000-BRITONS-day.html

Families in Scotland, to self-isolate for 10 days if one member tests positive,

regardless of their vaccination status and even if they initially get a negative PCR test

UK Government working on a 'Plan C'

UK, Health Security Agency

https://twitter.com/UKHSA/status/1468951053903142913?ref_src=twsrc%5Egoogle%7Ctwcamp%5Eserp%7Ctwgr%5Etweet

https://www.gov.uk/government/news/covid-19-variants-identified-in-the-uk

Omicron is displaying a significant growth advantage over Delta,

likely to outcompete Delta in the UK and become the dominant variant.

If the growth rate and doubling time continue,

at least 50% of coronavirus (COVID-19) cases to be caused by Omicron variant by mid-December

One million by end of December

1% = 10,000

Omicron displays a reduction in protection offered by having had a previous infection or vaccination.

There is insufficient data to make any assessment of protection against severe disease,

or to assess the severity of illness caused by Omicron.

Further studies are underway in the UK and abroad.

https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/1039644/Omicron_SGTF_case_update_FINAL.pdf

https://www.gov.uk/government/publications/investigation-of-sars-cov-2-variants-technical-briefings

Graph refs

https://ourworldindata.org/coronavirus

SA. Live data, hospital patients who have tested positive

https://www.nicd.ac.za/diseases-a-z-index/disease-index-covid-19/surveillance-reports/daily-hospital-surveillance-datcov-report/

South Africa references

https://www.nicd.ac.za/diseases-a-z-index/disease-index-covid-19/sars-cov-2-genomic-surveillance-update/

Weekly deaths in SA

https://www.samrc.ac.za/reports/report-weekly-deaths-south-africa

Variants in SA

https://www.worldometers.info/coronavirus/country/south-africa/

https://www.gov.uk/government/publications/sage-98-minutes-coronavirus-covid-19-response-7-december-2021/sage-98-minutes-coronavirus-covid-19-response-7-december-2021

Hospital admissions from Omicron should be expected to follow soon (high confidence).

Though there remain some important uncertainties,

Early verbal reports indicate that hospitalisations due to Omicron are now increasing in South Africa.

The doubling time for new Omicron infections is currently around 3 days in England

It is unlikely to be any slower than a 5-day doubling time (high confidence)

Household studies show higher secondary attack rates (high confidence).

Why is omicron more transmissible?

Combinations of transmissibility and immune escape

Some early indications from South Africa suggest less severe disease in those hospitalised

A modest reduction in severity would not avert high numbers of hospitalisations if growth rates remained very high.

One thousand per day be end of month

The peak is highly likely to be higher than 1,000 to 2,000 Omicron hospital admissions per day without intervention

For it to be below this level there would need to be only a small degree of immune escape and very high protection from boosters against Omicron

With very rapid doubling times a large wave could occur leading to synchronous absences from work.

With lags of the order of two or more weeks,

and doubling times Learn more about your ad choices. Visit megaphone.fm/adchoices

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