JAMA Guide to Statistics and Methods: Assessing Unexpected Circumstances That Lead to Modifications in Clinical Trial Design, Conduct, or Analysis With Professor Brooks

Michelle A. Detry, PhD, Berry Consultants LLC, discusses The Intention-to-Treat Principle: How to Assess the True Effect of Choosing a Medical Treatment with JAMA Statistical Editor Roger J. Lewis, MD, PhD.

Roderick Little, PhD, University of Michigan School of Public Health Departments of Epidemiology & Biostatistics discusses Pattern-Mixture Models for Missing Data with Roger J. Lewis, MD, PhD, statistical editor for JAMA.

Kert Viele, PhD, director and senior statistical scientist at Berry Consultants, discusses "Interpretation of Clinical Trials That Stopped Early" with JAMA Statistical Editor Roger J. Lewis, MD, PhD.

Natalie Exner Dean, PhD, Associate Professor, Rollins School of Public Health, Emory University, discusses Test-Negative Study Designs for Evaluating Vaccine Effectiveness with JAMA Statistical Editor Roger J. Lewis, MD, PhD.

Steve A. Webb, MBBS, MPH, PhD, professor, Royal Perth Hospital, The University of Western Australia discusses Platform Clinical Trials for the Efficient Evaluation of Multiple Treatments with JAMA Statistical Editor Roger J. Lewis, MD, PhD.