#96 - Interview with John Klepper - Serial Entrepreneur, Board Member, Strategist, Innovator, Speaker and founder

🎙️ CapricornConnect Podcast – New Episode

Delirium is one of the most devastating, and overlooked, conditions in healthcare. Affecting nearly 1 in 4 hospital patients over the age of 60, it can lead to hallucinations, cognitive decline, longer hospital stays, and permanent loss of independence. Yet in many cases, it is preventable.

In this episode of the CapricornConnect Podcast, we speak with John Klepper, serial entrepreneur and Founder & CEO of PIPRA, about how AI is transforming delirium prevention in hospitals worldwide.

John’s journey into healthcare innovation is deeply personal. After working in Alzheimer’s prevention, his own mother experienced delirium during a hospital stay—an event she later described as the most terrifying experience of her life. That moment inspired the creation of PIPRA’s non-pharmacological, AI-based technology, which predicts delirium risk before onset and enables proactive care pathways.

Proven hospital results include: - Switzerland: 29% reduction in delirium cases - Spain (Madrid): 43% reduction - Germany (Munich): 72% reduction

Beyond patient outcomes, delirium carries enormous economic costs—exceeding those of diabetes—driven by longer stays, readmissions, and complications.

We also discuss: - John’s unconventional path from the film industry (The Matrix) to health tech - Why culture and intuition matter more than perfect CVs when building teams - The emotional realities of entrepreneurship - Why empathy is a critical leadership skill in the age of AI

This episode explores how AI, when built with empathy and evidence, can save lives and reshape healthcare systems.