The Dr. Josh Axe Show

Health Experts Reveal What’s REALLY Making You Sick | Roundtable

The Dr. Josh Axe Show

Show Notes

Your hormones, your sleep, your stress, your diet — they may all be affecting your health at a much deeper level than you realize. Dr. Josh Axe sits down with functional medicine expert Dr. Will Cole and fitness and biohacking educator Dylan Gemelli for a no-holds-barred roundtable on what may actually be driving chronic disease, accelerated aging, hormonal dysfunction, and poor metabolic health — and why healing may need to start at the cellular level. In this episode, we learn why Dr. Axe and Dr. Cole believe cellular health could change how we approach chronic disease — and how to identify which systems in your body may be aging faster than others.Uncover what’s really going on in your body with advanced biomarker testing for hormones, thyroid, and metabolism — plus a 1-hour consultation with a Senior Health Advisor! → http://mybloodwork.com Disclaimer: The bloodwork our team runs at mybloodwork.com covers a handful of the biomarkers listed in the guide above — including critical thyroid and metabolic markers — plus a 1-hour consultation with a Senior Health Advisor, but does NOT cover all 25. You will want to consult your primary or functional doctor for the entire list.

Thank you to our sponsors! Sunlighten Sauna → https://get.sunlighten.com/axepodcast Manukora Manuka Honey → https://manukora.com/axe Watch The Dr. Josh Axe Show every Monday & Thursday on YouTube → https://www.youtube.com/@drjoshaxe?sub_confirmation=1 🎧 **Early Access!** Our listeners enjoy every episode before anyone else! Tune in below and join our exclusive group of listeners → Spotify → https://bit.ly/DrJoshAxeSpotify Apple Podcasts → https://apple.co/3JDvWcS Order our NEW BOOK, *Heal Your Cells* → healyourcellsbook.com Watch my free training on how to naturally balance your blood sugar and reverse your symptoms → http://DrAxeDiabetesClass.com Discover practical steps you can take today to start healing your thyroid naturally → http://DrAxeThyroidClass.com If you’re ready to start feeling like yourself again and balance your hormones, take my free class → http://DrAxeHormoneClass.com CONNECT WITH DR. JOSH AXE Instagram → https://www.instagram.com/drjoshaxe/ Facebook → https://www.facebook.com/DrJoshAxe/ TikTok → https://www.tiktok.com/@thedrjoshaxeshow/ X → https://x.com/drjoshaxe/ LinkedIn → https://www.linkedin.com/in/joshaxe Website → http://thehealthinstitute.com Sign up for my newsletter → https://bit.ly/4oE9Jf3 Ask Dr. Axe → http://speakpipe.com/drjoshaxe CONNECT WITH DR. WILL COLE Website → https://drwillcole.com Instagram → https://www.instagram.com/drwillcole/ Podcast → The Art of Being Well CONNECT WITH DYLAN GEMELLI Website → https://dylangemelli.com Instagram → https://www.instagram.com/dylangemelli/ YouTube → https://www.youtube.com/@DylanGemelliBiohacking Podcast → The Dylan Gemelli Podcast TIMESTAMPS: 00:00 — The Biggest Drivers of Chronic Disease 02:29 — Welcome to the Health & Longevity Roundtable 03:07 — Why Cellular Health May Be the Future of Medicine 06:10 — Is One of Your Organs Aging Faster Than the Rest? 08:22 — How Early Do Health Problems Really Begin? 12:30 — The Blood Markers That Could Reveal Heart Disease Risk 18:12 — What Insulin Resistance Actually Means 19:59 — The 2 Hormones That Can Throw Everything Off 22:58 — The Surprising Connection Between Sleep & Insulin Resistance 25:10 — “I’ll Sleep When I’m Dead” Is Destroying Your Health 31:32 — Waking Up at 3 A.M.? Cortisol May Be the Reason 32:43 — How to Lower Stress & Support Your Vagus Nerve 37:18 — How Your Mind & Nervous System Affect Your Health 41:32 — Can Childhood Trauma Keep You From Healing? 43:55 — Forgiveness, Faith & the Nervous System 48:11 — Why Dylan Believes Health Starts With “Mind, Body & God” 51:11 — Can Faith Actually Help You Live Longer? 58:35 — The Truth About Peptides & Where Medicine Is Headed 1:03:29 — Are Peptides Overhyped or the Future of Health? 1:05:31 — Conventional vs. F

More from The Dr. Josh Axe Show

Oct 22, 2026

Jordan Rubin healed himself of Crohn's disease, ulcerative colitis, and cancer using food as medicine — and the foods that saved his life are ones most people have never considered putting on their plate. In this conversation, Jordan and Dr. Axe walk through more than 20 underused healing foods, from organ meats and glandulars packed with natural peptides, to ancient fermented foods like kefir and natto, to wild berries consumed by the world's longest-lived cultures. Each food comes with the science, the history, and practical ways to actually use it.

Oct 19, 2026

The belly fat you can’t pinch may matter more than the number on your scale. In this episode, Dr. Axe explores visceral fat—the fat surrounding your internal organs—and seven foods studied for their potential to help reduce it. He breaks down an 18-month trial that measured a 14.1% reduction in visceral fat versus 4.2% with general healthy eating, plus research on fermented milk, eggs, green tea, and more. You’ll also hear his recommended daily plate, with practical portions to help you get started. Download my FREE Guide for Your 7-Day Plate: https://guide.thehealthinstitute.com/l-413

Oct 15, 2026

Could inflammation be contributing to your brain fog, fatigue, and joint pain? Dr. Josh Axe sits down with Ayurvedic practitioner Dr. Shivani Gupta to explore chronic inflammation and its connection to aging, gut health, and menopause. They discuss turmeric, boswellia, and other Ayurvedic herbs, plus practical ways to bring more spices, seasonal foods, and variety into your daily meals.

Oct 12, 2026

Tired, bloated, or struggling with stubborn belly fat? Dr. Josh Axe explores how inflammation may contribute and shares a five-part protocol used in a 12-week study of 110 people. Learn about food, movement, spiritual practices, supplements, and a simple daily habit—plus how to measure inflammation and track your progress.

Oct 8, 2026

Stasi Eldredge thought she’d had an ideal childhood—until her husband, John, told her, “You're raging and it's hurting our children.” His honesty sparked a journey toward healing the wounds she hadn’t recognized.

See all episodes →