
Producing Beta Cells: Generation of Pancreatic islets from Stem Cells
Diabetes Insights - Breakthroughs and InnovatorsShow Notes
Today on Diabetes Insights, Prof. Raphael Scharfmann (INSERM, France) and Dr. Valeria Sordi (San Raffaele Diabetes Research Institute, Italy) join our host, Vivienne Parry to discuss the progress and remaining challenges in creating functional, insulin-producing beta cells from stem cells.
From the fundamental biology of pancreatic development to translational protocols for generating clinical-grade cells, our experts highlight how far the field has advanced and what hurdles remain before cell replacement therapies become a routine option for people with diabetes. They explore key questions around immune rejection, scalability, long-term viability of transplanted cells, and how the research community is navigating the complexities of cell manufacturing at clinical scale.
Listen now for a fascinating look at how cutting-edge science is shaping the future of cell-based therapies in diabetes care.
More from Diabetes Insights - Breakthroughs and Innovators
In this EASD TV interview, Prof. Zachary Gerhart-Hines (Novo Nordisk Foundation Center for Basic Metabolic Research), 61st EASD Minkowski Prize recipient, discusses research into the neurokinin-2 receptor (NK2R) and its potential to change how we approach weight management and metabolic health. Where many existing treatments focus on reducing food intake, NK2R activation could offer a complementary strategy by increasing energy expenditure, influencing appetite and improving insulin sensitivity.
How does exercise stimulate glucose uptake in muscle and what can this teach us about treating type 2 diabetes?
Prof. Anette-Gabriele Ziegler, this year’s Claude Bernard Prize Lecture recipient, reflects on her career in type 1 diabetes research and the evolution of our understanding of the disease.
The EASD’s first clinical practice guideline on the assessment and management of diabetes distress in adults living with type 1 or type 2 diabetes has now been published in Diabetologia.
How can people living with diabetes help shape the future of diabetes care?