
Show Notes
Omar Santos is a Distinguished Engineer directing AI Security at Cisco. He’s here for a frank conversation about the realities of security in the agentic era. As more software is created on-the-fly by AI agents at the request of humans, security has to become an ever-present layer. Security will be built into complete agent runtime environments and will require constant human oversight and intervention, augmented by the ability to simulate outcomes to avoid risk.
Omar is also the Co-Chair of the Coalition for Secure AI, and these are the things he’s thinking about on a daily basis. He sits down with Robb and Josh at the end of a travel blitz that included work surrounding OpenAI’s Stargate Project, a four-year $500b plan for new AI infrastructure in the United States. The trio discuss how the ongoing training of models and the rising demand for inference continue to push the demand for security across burgeoning technology ecosystems.
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Chapters - 00:00 - Intro and episode setup 00:33 - Meet Omar Santos and his role in AI security 01:00 - Security as the new programming 02:20 - Coalition for Secure AI and security as a new language 04:45 - Identity, access, and AI agents 06:09 - Scaling models and mega data centers 09:04 - Training vs inference and the compute explosion 12:54 - Budgets, compute, and hybrid human–AI security teams 15:16 - Checklists, guardrails, and spec-driven development 20:00 - From IDEs to agent swarms and background agents 25:19 - CodeGuard, rules for coding agents, and secure SDLC 32:00 - Why doing nothing is the biggest AI security risk 39:30 - Validating AI, AI safety levels, and open source dilemmas 46:00 - Private networks, insider AI agents, and embedded security 51:00 - Simulation, digital twins, and business-wide risk modeling
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