Hormones, Metabolism & You!

101: Fix Your Gut, Fix Your Hormones: The Missing Links When Thyroid + Hormones Aren’t Enough

Hormones, Metabolism & You!

Show Notes

>>Join our FREE monthly Gut Health Webinar, so you can begin your Healing Journey.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://modernendocrinewellness.com/join-gut-health⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠<<

What if the reason you still feel tired after optimizing hormones is not your hormones at all?

In this episode of Hormones, Metabolism, and You, Dr. Cassie Smith sits down with Dr. Terri DeNeui in Destin, Florida during an advanced hormone provider refresher to talk about the most common issue clinicians see after “optimizing hormones”: patients still feel tired, foggy, inflamed, or stuck. They break down why “normal” labs are not the same as optimal, why Free T3 matters, and how deficiencies in vitamin D, B12, and ferritin can block thyroid hormone function and keep symptoms alive. You will also hear how gut inflammation, H. pylori, and chronic acid blockers can sabotage hormone metabolism, why many “side effects” blamed on hormones are actually root-cause problems, and how to spot misinformation about estrogen and testosterone, especially for women.

About Dr. Terri DeNeui

Dr. Terri DeNeui, DNP, APRN, ACNP-BC, is a board-certified nurse practitioner, nationally recognized speaker, author, and the founder of EvexiPEL® and Evexia Medical. She holds advanced training in hormone replacement, preventive wellness, and functional medicine, and is known for her root-cause approach to optimizing hormones and whole-body health. Through her clinical work and provider education, Dr. DeNeui has helped transform the lives of thousands of patients and trained clinicians across the country. She is also the author of Hormone Havoc, a practical guide that clears up myths and misconceptions about hormones in women and men.

Key Topics Covered

Why patients can still feel “off” even when hormones look optimized

The thyroid lab most clinicians miss: Free T3

Why “normal” lab ranges often reflect a sick population, not optimal health

Vitamin D, B12, and ferritin: the hidden drivers behind fatigue, brain fog, and poor thyroid response

Ferritin and thyroid hormone: why low ferritin can block hormone function at the cellular level

Gut root causes behind low iron: heavy bleeding, hormone metabolism issues, H. pylori, and inflammation

Why chronic PPI use can worsen nutrient absorption and hormone conversion

Misconceptions about estrogen and cancer, and why metabolism and inflammation matter

Misconceptions about testosterone in women, plus why dosing and proper oversight change outcomes

Why hormone care works best when you treat the body as a system of systems

Resources & Links

🌐 Dr. Terri DeNeui LinkedIn: https://www.linkedin.com/in/terri-deneui/📚 Book: Hormone Havoc: Dispelling the Myths and Misconceptions about Hormones in Women and Men – https://a.co/d/02qh7exW

📲 Follow Dr. Cassie Smith & Modern Endocrine

💻 Website:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.modern-endocrine.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

📸 Instagram:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.instagram.com/modernendocrine_/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

🌟 Facebook:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.facebook.com/ModernEndocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

📽️ YouTube:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.youtube.com/@modernendocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

🕹️ TikTok:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.tiktok.com/@modernendocrine?lang=en⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

📰 Newsletter:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://linktr.ee/modernendocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠

➡️ Disclaimer:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.modernendocrineokc.com/disclaimer-6353⁠

More from Hormones, Metabolism & You!

Oct 18, 2026

Dr. Anna Cabeca joins me to talk about why so many midlife women are told their labs are normal while they feel exhausted, foggy, and out of step with their own bodies. We talk about what shifts in perimenopause, how falling progesterone and insulin resistance can show up as everyday symptoms, and why Dr. Cabeca treats hormone imbalance as a metabolic question first.

Oct 11, 2026

What if I told you right now, this very moment, your body is carrying a chemical load that you have never been tested for, never been warned about, and never asked for? In this episode, I’m joined by Nick Pineault, author of The Non-Tinfoil Guide to EMF and creator of the documentary Body Burden: The Toxins We Carry, to talk about what “body burden” actually means and how the chemicals we encounter through our food, water, air, plastics, household products and technology may intersect with hormones, metabolism and overall health.

Oct 4, 2026

Dr. Monisha Bhanote joins me to talk about cellular health and resilience, and why fatigue, brain fog, digestive issues, and other everyday symptoms may be signals from our cells rather than things we should simply accept. We talk about her approach to cell care, cellular consciousness, and why health practices need to be personalized rather than copied from the latest trend.

Sep 27, 2026

What happens when you’re doing all the “right” things for your hormones and health, but you still don’t feel better? In this episode, I sit down with Dr. Neil Nathan to explore why underlying factors like mold, Lyme disease, inflammation, nervous system dysregulation, and detoxification challenges may complicate treatment.

Sep 20, 2026

Testosterone in women is finally getting more attention, but what does that actually mean for women and their care? In this episode, I sit down with Dr. Terri DeNeui to discuss the FDA’s focus on testosterone, why there still isn’t an FDA-approved testosterone treatment specifically for women, and the questions surrounding safety, dosing, and access.

See all episodes →