Episode 502: Prozac (Fluoxetine) and Other Drugs That Injure Endothelium
Heart Doc VIP with Dr. Joel KahnShow Notes
This week, Dr. Kahn reviews important new research showing that the commonly prescribed antidepressant Prozac (fluoxetine) may disrupt cholesterol metabolism, injure the endothelium (the delicate lining of arteries), and potentially increase cardiovascular risk. He also examines growing evidence linking proton pump inhibitors (PPIs) and several common cancer therapies to endothelial damage, emphasizing that patients should always discuss the risks and benefits of these medications with their healthcare team rather than stopping treatment on their own. Other topics include new Harvard research showing that combining aerobic exercise, strength training, and less time spent watching television can reduce the risk of type 2 diabetes by up to 60%; promising data on niacin for glioblastoma brain cancer; predicting statin-related muscle injury; the protective effects of plant-based diets against heart disease, dementia, and several cancers; tea consumption and lower cardiovascular risk; vitamin K-rich leafy greens and lung health; whole grains and breast cancer prevention; and the latest research on red meat, inflammatory bowel disease, and hypertension. Thanks to igennus.com/drkahn for this week's podcast sponsorship featuring their vegan Super B Complex.
More from Heart Doc VIP with Dr. Joel Kahn
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This week, Dr. Kahn presents a new scientific statement by the American College of Cardiology on nutrition to prevent heart disease. The emphasis is on plant-based choices while limiting red meat, processed foods, and excess added sugar. Sometimes, hearing the same recommendation over and over can help.
This week, as a bonus, Dr. Kahn interviews a Detroit clothing legend, Phil, who celebrated his 100th birthday recently by buying a new sports car! He is approaching his 78th wedding anniversary with his beautiful wife. He discussed his early days in business and early successes, and his health journey, relying a lot on the education he got by repeatedly visiting the Pritikin Longevity Center.
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