NEI Podcast

E249 - Unintended Effects of FDA Pediatric Antidepressant Boxed Warnings with Christine Moutier, MD

NEI Podcast

Show Notes

Join Dr. Andy Cutler as he speaks with Dr. Christine Moutier about the unintended effects of the FDA boxed warnings on antidepressant use in pediatric patients—specifically, the underdiagnosis and undertreatment of depression. Their conversation highlights the importance of effectively treating depression to reduce suicide across the lifespan.

Christine Yu Moutier, MD is a leading psychiatrist and the Chief Medical Officer at the American Foundation for Suicide Prevention (AFSP). Since joining AFSP in 2013, Dr. Moutier has led a nationwide movement combining scientific research and grassroots efforts to reduce suicide rates. She has testified before Congress, presented at the White House, and frequently contributes to major media outlets on mental health issues.

Andrew J. Cutler, MD is a distinguished psychiatrist and researcher with extensive experience in clinical trials and psychopharmacology. He currently serves as the Chief Medical Officer of Neuroscience Education Institute and holds the position of Clinical Associate Professor of Psychiatry at SUNY Upstate Medical University in Syracuse, New York.

Resources

American Foundation for Suicide Prevention - https://afsp.org/

Save $100 on registration for 2025 NEI Spring Congress with code NEIPOD25 Register today at nei.global/spcongress25f

Never miss an episode!🎙SUBSCRIBE to the NEI Podcast– available on all your favorite platforms: https://nei.global/podcast

Interested in Psychopharmacology? Learn about the NEI Master Psychopharmacology Program: https://nei.global/mpp

Stay updated with email alerts and join our conversations on social. Follow us on:

YouTube: https://nei.global/youtube

Instagram: https://nei.global/instagram

LinkedIn: https://nei.global/linkedin

Facebook: https://nei.global/facebook

X: https://nei.global/twitter

More from NEI Podcast

Oct 21, 2026

In this episode, Dr. Andy Cutler talks with Dr. Jon Grant about how compulsivity presents across obsessive-compulsive disorder (OCD), trichotillomania, and skin-picking disorder (excoriation disorder). They discuss how clinicians can distinguish OCD compulsions from body-focused repetitive behaviors and choose among treatments such as exposure and response prevention, habit-reversal training, medication, and emerging treatment approaches.

Oct 7, 2026

Originally released in 2022, this episode of The PsychopharmaStahlogy Show features Drs. Andrew Cutler and Stephen Stahl in conversation with Dr. Tiffany Greenwood on the genetic and trait-based links between bipolar disorder and creativity. They explore how temperament, personality, and cognitive style may occupy the space between madness and genius, the role of dopamine, evolutionary explanations for why bipolar risk persists, and why stabilizing mood doesn't have to mean losing creativity.

Sep 23, 2026

Originally released in 2024, this episode features the late Dr. Vladimir Maletic in conversation with Drs. Andy Cutler and Stephen Stahl about the clinical significance and neurobiology of anhedonia. They discuss its different dimensions, how it differs from emotional blunting, its relationship to functioning and treatment response, and practical approaches to assessment and treatment. The episode highlights why recovery from depression requires restoring interest, motivation, and pleasure—not simply reducing negative symptoms.

Sep 9, 2026

In this episode, Dr. Andy Cutler speaks with Dr. Tim Wilens about the complex relationship between attention-deficit/hyperactivity disorder (ADHD) and substance use disorders. They discuss how to distinguish ADHD from substance-related cognitive symptoms, determine when co-occurring conditions should be treated concurrently, and select appropriate ADHD medications based on the substance involved. Dr. Wilens also examines stimulant misuse and diversion, the role of nonstimulants, what is known about centanafadine's abuse potential, and practical approaches to monitoring treatment without undermining the therapeutic relationship.

Aug 26, 2026

Originally released in 2021, this episode features Dr. Thomas Schwartz discussing common mistakes in psychopharmacology and how psychiatric clinicians can recognize and manage them. He explores diagnostic uncertainty, medication dosing, informed consent and monitoring, and rational versus irrational polypharmacy. He also considers how clinicians can reassess inherited diagnoses, learn from prescribing errors, and preserve the therapeutic relationship when mistakes occur.

See all episodes →