Nicole C. Nelson, "Model Behavior: Animal Experiments, Complexity, and the Genetics of Psychiatric Disorders" (U Chicago Press, 2018)
New Books in NeuroscienceShow Notes
Mice are used as model organisms across a wide range of fields in science today--but it is far from obvious how studying a mouse in a maze can help us understand human problems like alcoholism or anxiety. How do scientists convince funders, fellow scientists, the general public, and even themselves that animal experiments are a good way of producing knowledge about the genetics of human behavior? In Model Behavior: Animal Experiments, Complexity, and the Genetics of Psychiatric Disorders (U Chicago Press, 2018), Nicole C. Nelson takes us inside an animal behavior genetics laboratory to examine how scientists create and manage the foundational knowledge of their field.
Behavior genetics is a particularly challenging field for making a clear-cut case that mouse experiments work, because researchers believe that both the phenomena they are studying and the animal models they are using are complex. These assumptions of complexity change the nature of what laboratory work produces. Whereas historical and ethnographic studies traditionally portray the laboratory as a place where scientists control, simplify, and stabilize nature in the service of producing durable facts, the laboratory that emerges from Nelson's extensive interviews and fieldwork is a place where stable findings are always just out of reach. The ongoing work of managing precarious experimental systems means that researchers learn as much--if not more--about the impact of the environment on behavior as they do about genetics. Model Behavior offers a compelling portrait of life in a twenty-first-century laboratory, where partial, provisional answers to complex scientific questions are increasingly the norm. Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/neuroscience
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Once dismissed as unscientific, psychoanalytic therapy is proving to be among our most effective medical treatments of any kind - outperforming psychiatric drugs and rivaling vaccines in its power to prevent and heal. Why does it work so well?Perhaps because one of the most controversial figures in psychology was right all along. Neuroscience now confirms much of what Sigmund Freud conjectured over a century ago: our deepest struggles stem, not from chemical imbalances, but from buried memories and unconscious conflicts that no pill can touch.Using enthralling case studies and cutting-edge brain science, pioneering neuroscientist Mark Solms makes the case that psychoanalysis should resume its position as our master theory of the mind. Yet modern research also reveals where Freud got important things wrong. Could correcting these errors make therapy even more effective?As psychiatric diagnoses soar and standard treatments continue to fail many patients, The Only Cure: Freud and the Neuroscience of Mental Healing (Pegasus, 2026) offers a revolutionary hope: a real science of healing, rooted in the radical idea that our suffering arises from truths we haven't yet faced. Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/neuroscience
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