Show Notes
JACCP associate editor and host, Erica Ernst, interviews Drs. Wendy St. Peter and Barbara Zarowitz discuss adopting race-free estimated GFR (CKD-EPI) for medication-related kidney function assessment in older adults and other patient populations, as well as moving away from the Cockcroft–Gault equation. The discussion highlights deficiencies and variabilityin Cockcroft–Gault use, emerging studies where BSA-adjusted eGFR better predicts drug clearance, barriers to cystatin C access and Medicare coverage, and the need for further research, electronic health record integration, and advocacy across organizations. Read the original article and series of letters published in JACCP.
More from ACCP JOURNALS
Dr. Janelle Perkins, guest editor for the themed issue on Women’s Health in Oncology highlights cancer care challenges specific to women across life stages (menarche, pregnancy, breastfeeding, menopause), including infertility, early menopause, fetal/newborn risks, contraception, and menopausal care, and emphasizes individualized, goal-driven patient–provider discussions. They discuss fertility and reproductive management during treatment, differences among cytotoxic chemotherapy, hormonal agents such as aromatase inhibitors, targeted therapies, and immune checkpoint inhibitors, and communication to clarify expectations and side effects. Perkins summarizes emerging observational data on GLP-1 receptor agonists during breast cancer treatment, including possible cardioprotective benefits amid GI side-effect concerns. Read the full issue at: https://accpjournals.onlinelibrary.wiley.com/doi/toc/10.1002/(ISSN)1875-9114.womens-health-in-oncology
Are clinical metrics measuring what actually matters? In this episode, JACCP Editor-in-Chief Stuart Haines and new Associate Editor Ty Kiser sit down with Andrea Sikora and Brian Murray (University of Colorado) to discuss their editorial "Keeping the Good in Goodhart's Law: Bridging Key Performance Indicators to Comprehensive Medication Management," written in response to the Clinical Administration PRN Opinion Paper that proposes 15 key performance indicators (KPIs) for clinical pharmacy practice. Drawing on Goodhart's Law and McNamara's Fallacy, Sikora and Murray warn that easy-to-measure tasks like IV-to-PO conversion can crowd out the harder-to-quantify cognitive work of comprehensive medication management (CMM). Using vivid stories from the ICU, they make the case for pairing pharmacist-facing KPIs with structural accountability measures that protect time for the work that matters most.
This episode focuses on missed opportunities to intensify lipid-lowering therapy, highlighting gaps where treatment escalation could improve lipid management and cardiovascular risk reduction. The discussion centers on recognizing when lipid control is inadequate and on the role of the clinical pharmacist in optimizing medications, including PCSK9i, statins, and emerging therapies, to better align with patient risk and treatment goals. Read the full article at: https://accpjournals.onlinelibrary.wiley.com/doi/10.1002/jac5.70209
Drs. Shannon Finks and Sarah McBane discuss their July 2026 narrative review, “Menopausal Hormone Therapy: A Narrative Review of Contemporary Evidence.” They describe menopause as a multisystem transition with vasomotor, mood/cognitive, cardiometabolic, and genitourinary symptoms, noting many women see multiple clinicians before diagnosis. They emphasize that menopausal hormone therapy (MHT) formulation, route, timing, and patient selection matter. They discuss MHT benefits for symptom relief, bone protection, and genitourinary symptoms, nuances around cardiovascular, cancer, and cognition outcomes, FDA labeling updates, and more. The manuscript is available at: https://accpjournals.onlinelibrary.wiley.com/doi/10.1002/phar.70178
Artificial intelligence (AI) is reshaping how research gets done — and pharmacy practice is no exception. In this episode, Editor-in-Chief Stuart T. Haines sits down with Katie Trinkley, Associate Professor of Medicine at the University of Colorado School of Medicine. Dr. Trinkley recently authored an invited paper in JACCP on Research and Scholarly Methods series regarding the use of AI, and she joins us to unpack what pharmacy researchers need to know right now. From the fundamental differences between predictive and generative AI, to the build-versus-buy decision, to AI's underappreciated role in qualitative research, this conversation offers a practical, rigorous framework for using AI thoughtfully — and why pharmacists are uniquely positioned to lead the way. Read the full manuscript: https://accpjournals.onlinelibrary.wiley.com/doi/10.1002/jac5.70239