Therapeutic cannabis with Professor Brighthope

Impact of Delta on viral burden and vaccine effectiveness against new SARS-CoV-2 infections in the UK Uploaded 19-08-21https://www.ndm.ox.ac.uk/covid-19/covid-19-infection-survey/results/new-studieshttps://www.ndm.ox.ac.uk/files/coronavirus/covid-19-infection-survey/finalfinalcombinedve20210816.pdfN = 384,543Households, 221,909Obtaining two vaccine doses remains the most effective way to ensure protection against Delta With Delta, Pfizer-BioNTech and Oxford-AstraZeneca vaccines still offer good protection against new infectionsbut effectiveness is reduced compared with AlphaHowever, Delta infections after two vaccine doses had similar peak levels of virus to those in unvaccinated people(with the Alpha variant, peak virus levels in those infected post-vaccination were much lower)Two doses of either vaccine still provided at least the same level of protection as having had COVID-19 through natural infectionPeople who had been vaccinated after already being infected with COVID-19 had even more protection than vaccinated individuals who had not had COVID-19 beforeTwo doses of Pfizer-BioNTech have greater initial effectiveness against new COVID-19 infectionsbut this declines faster compared with two doses of Oxford-AstraZenecaAfter four to five months, effectiveness of these two vaccines similarhowever, long-term effects need to be studiedThe time between doses does not affect effectiveness in preventing new infectionsYounger people have even more protection from vaccination than older peopleUK, third shotshttps://www.bbc.co.uk/news/live/uk-58266043Prof Peter OpenshawNew and Emerging Respiratory Virus Threats Advisory Group (NERVTAGWe can't just look at the antibody levels and think that that equates to levels of protectionIt still seems that you get a lot of protection from these vaccines, even if the antibody levels have drifted down to some sort of stable level Learn more about your ad choices. Visit megaphone.fm/adchoices Learn more about your ad choices. Visit megaphone.fm/adchoices

Please share this video, this research must STOP. Gain of function research in the USA today using enhanced potential pandemic pathogen (ePPP) researchUploaded 22-10-22Professor Shmuel Shapira, lead scientist, Israeli Governmenthttps://www.dailymail.co.uk/health/article-11323677/Outrage-Boston-University-CREATES-Covid-strain-80-kill-rate.htmlThis should be totally forbidden, it's playing with fireDr Richard Ebright, Rutgers University, New BrunswickThe research is a clear example of gain of function research.If we are to avoid a next lab-generated pandemic, it is imperative that oversight of enhanced potential pandemic pathogen research be strengthened.it is imperative that officials at US-government agencies,who repeatedly have placed the public at risk by repeatedly violating the existing policies be held accountableProf David Livermore, microbiology, University of East Angliagiven the strong likelihood that the Covid pandemic originated from the escape of a lab-manipulated coronavirus in Wuhan, these experiments seem profoundly unwiseBoston University's National Emerging Infectious Diseases Laboratories is one of 13 biosafety level 4 labs in the USRole of spike in the pathogenic and antigenic behavior of SARS-CoV-2 BA.1 Omicron14th October 2022Boston University School of Medicinehttps://www.biorxiv.org/content/10.1101/2022.10.13.512134v1Predominant SARS-CoV-2 Omicron variant (BA.1) is highly transmissible, even in fully vaccinated individuals, and causes attenuated disease compared with other major viral variants recognized to dateThe Omicron spike (S) protein, unusually large number of mutations, is considered the major driver of these phenotypesWe generated chimeric recombinant SARS-CoV-2A chimera or chimeric virusOne virus containing genetic material derived from two or more distinct virusesUS Center for Veterinary Biologicshttps://www.aphis.usda.gov/animal_health/vet_biologics/publications/notice_05_23.pdfA new hybrid microorganism,created by joining nucleic acid fragments from two or more different microorganisms,in which each of at least two of the fragments,contain essential genes necessary for replication We generated chimeric recombinant SARS-CoV-2Encoding the S gene of Omicron in the backbone of an ancestral SARS-CoV-2 isolate,and compared this virus with the naturally circulating Omicron variant. The Omicron S-bearing virus robustly escapes vaccine-induced humoral immunity, mainly due to mutations in the receptor-binding motif,yet unlike naturally occurring Omicron, efficiently replicates in cell lines and primary-like distal lung cells. In K18-hACE2 micehttps://www.jax.org/strain/034860K18-hACE2 transgenic mice express human ACE2, including airway epithelia where infections typically begin. Because K18-hACE2 are susceptible to SARS-CoV-2 and SARS-CoV viruses, they are useful for studying antiviral therapies to COVID-19 and SARS.In K18-hACE2 miceOmicron causes mild, non-fatal infection, the Omicron S-carrying virus inflicts severe disease with a mortality rate of 80%. This indicates that while the vaccine escape of Omicron is defined by mutations in S, major determinants of viral pathogenicity reside outside of S.Frankenstein, Mary Shelley, 1818Frightful must it be; for supremely frightful would be the effect of any human endeavour to mock the stupendous mechanism of the Creator of the world (1831 edition) Learn more about your ad choices. Visit megaphone.fm/adchoices Learn more about your ad choices. Visit megaphone.fm/adchoices

Scotland, mask mandatesUploaded 16-03-22https://www.telegraph.co.uk/news/2022/03/15/scotland-keep-face-masks-another-two-weeks-due-spike-cases/?WT.mc_id=e_DM1551567&WT.tsrc=email&etype=Edi_GHS_New_Daily&utmsource=email&utm_medium=Edi_GHS_New_Daily20220315&utm_campaign=DM1551567Nicola Sturgeon, “prudent” mandatory mask rules, until April 4 at the earliest.Mask rules, case numbers well ahead of Englandhttps://www.ons.gov.uk/peoplepopulationandcommunity/healthandsocialcare/conditionsanddiseases/articles/coronaviruscovid19/latestinsights2,073,900 people (1 in 25) in England97,900 people (1 in 30) in Wales143,800 people (1 in 13) in Northern Ireland299,900 people (1 in 18) in ScotlandCOVID-19: Why Are We Ignoring Infection-Acquired Immunity? https://www.medscape.co.uk/viewarticle/covid-19-why-are-we-ignoring-infection-acquired-immunity-2022a1000ifd?uac=127834AR&faf=1&sso=true&impID=4086722&src=mkm_ret_220315_mscpmrk_perspectiveuk_intAntibodies from natural infection, more abundant, more potent, at least 10 times more potent, than immunity generated by vaccination alone Hybrid immunity, induces a sort of 'super-immunity',irrespective of whether infection or vaccination comes first, there is increasing evidence that immunity derived from natural infection with COVID-19 gives powerful protection on its own. Natural immunity has been shown to be both highly protective and long lasting, and to safeguard against both re-infection and severe disease.Vaccination before or after SARS-CoV-2 infection leads to robust humoral response and antibodies that effectively neutralize variants(Oregon Health and Science University (OHSU) Portland, UShttps://www.science.org/doi/10.1126/sciimmunol.abn8014Antibody responses from the initial wave of vaccines in early 2021 have waned over 6 months,contributing to an increase in breakthrough infectionsWe measure neutralizing antibody responsesThose with breakthrough infections Hybrid immunityNo infection historyWe find that human immune sera After breakthrough infection and vaccinationAfter natural infectionbroadly neutralize variants to a similar degreeAge Negatively correlates with antibody response after vaccination alone, no correlation with age was found in breakthrough or hybrid immune groups. Together, our data suggest that the additional antigen exposure from natural infection substantially boosts the quantity, quality, and breadth of humoral immune response regardless of whether it occurs before or after vaccinationCOVID-19 Cases and Hospitalizations by COVID-19 Vaccination Status and Previous COVID-19 Diagnosis — California and New York, May–November 2021https://www.cdc.gov/mmwr/volumes/71/wr/mm7104e1.htmBy early October, persons who survived a previous infectionhad lower case rates than persons who were vaccinated alone.Natural immunity against COVID-19 significantly reduces the risk of reinfection: findings from a cohort of sero-survey participants (India)https://www.medrxiv.org/content/10.1101/2021.07.19.21260302v1.full.pdfstrong plausibility that development of antibody following natural infection not only protects against re-infection by the virus to a great extent,but also safeguards against progression to severe COVID-19 diseaseEU drug regulator expresses doubt on need for fourth booster dosehttps://www.reuters.com/business/healthcare-pharmaceuticals/eu-drug-regulator-says-more-data-needed-impact-omicron-vaccines-2022-01-11/European Medicines Agency, Head of Vaccines Strategy, Marco CavaleriWhile use of additional boosters can be part of contingency plans, repeated vaccinations within short intervals would not represent a sustainable long-term strategyBoosters every four months,poses the risk of overloading people's immune systems,and leading to fatigue in the population.There is a need fo Learn more about your ad choices. Visit megaphone.fm/adchoices

Learn more about your ad choices. Visit megaphone.fm/adchoicesUploaded 28-03-25 Learn more about your ad choices. Visit megaphone.fm/adchoices

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