
Ep 173 Ovarian Rejuvenation: The Race to Extend Fertility with Roohi Jeelani, MD
Brave & Curious with Dr Lora ShahineShow Notes
What if the "final frontier" of fertility care is not IVF technology, but the aging ovary itself? Can science help improve egg quality, mitochondrial function, and reproductive lifespan? And how do patients sort through what is proven, what is promising, and what is still very much in the "ask your doctor before you try this" category? In this episode of Brave & Curious, Dr. Lora Shahine welcomes reproductive endocrinologist Dr. Roohi Jeelani for a fascinating conversation about ovarian rejuvenation, age-related fertility decline, and the future of fertility treatment. Together, they discuss why age remains one of the biggest factors in IVF success, how egg quality changes over time, and why topics like oxidative stress, mitochondrial health, inflammation, and lifestyle optimization are becoming such important parts of the fertility conversation. In this episode you'll hear: [1:07] Meet Dr. Roohi Jeelani [2:32] Age and fertility [4:23] Egg quality basics [8:06] Sleep and fertility [9:35] Stress and cortisol [14:58] Movement and PCOS [16:54] Nutrition for fertility [18:51] Trimester zero prep: Small, sustainable changes [29:25] CoQ10, Inositol, Melatonin [35:38] NAD and egg quality [43:56] GLP-1 fertility questions [47:22] Peptides and PRP [55:33] Ovarian rejuvenation research [1:01:04] Future fertility medicine Resources mentioned: onto.health @roohijeelanimd on Instagram | LinkedIn @onto-health-co on LinkedIn Your Leggings Could be Causing Infertility? with Dr. Lora Shahine on YouTube Can CoQ10 Improve Egg Quality and Sperm Health for TTC? with Dr. Lora Shahine on YouTube Does Growth Hormone Improve IVF Outcomes? with Dr. Lora Shahine on YouTube
Dr. Shahine's Weekly Newsletter on Fertility News and Recommendations Follow @drlorashahine Instagram | YouTube | Tiktok | Her Books Join the Learn at Pinnacle app to earn FREE CE Credit for listening to this episode! This episode was produced by Audiotocracy Podcast Production.
More from Brave & Curious with Dr Lora Shahine
Has trying to conceive turned sex from something fun and spontaneous into another task on your fertility checklist? Are ovulation tracking, timed intercourse, and fertility treatments putting a strain on your relationship? How can you rebuild intimacy and sexual desire when infertility has taken the joy out of your sex life? In this episode of Brave & Curious, Dr. Lora Shahine welcomes Dr. Nicole McNichols, human sexuality expert, University of Washington professor, and author of You Could Be Having Better Sex, for an honest conversation about how infertility impacts sexual intimacy and relationships. Together, they explore why the pressure to conceive can decrease sexual desire, create tension between partners, and turn physical connection into a clinical process. From the emotional toll of negative pregnancy tests and IVF treatments to the challenges of timed intercourse, they discuss why maintaining intimacy while trying to get pregnant can feel so difficult. Dr. McNichols shares tips for reducing performance pressure, prioritizing nonsexual physical affection, and creating opportunities for intimacy outside the fertile window. They also discuss sexual dysfunction, painful intercourse, and when to seek support from a sex therapist or couples counselor. This episode offers compassionate, actionable advice to help you strengthen your relationship while trying to conceive. In this episode you'll hear: [2:29] How Infertility Impacts Sexual Desire [9:02] The Emotional Toll of Trying to Conceive [16:15] Sharing the Fertility Journey [20:56] Timed Intercourse and Performance Pressure [26:06] Infertility, Self-Blame, and Body Image [28:50] Rebuilding Sexual Intimacy [32:26] Sexual Dysfunction and Fertility [41:26] Painful Intercourse and Treatment Options [48:51] Strengthening Relationships During Infertility
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Can preeclampsia affect your health long after pregnancy ends? Does high blood pressure during pregnancy increase your future risk of heart disease or stroke? And what can you do now to protect your cardiovascular health? In this episode of Brave & Curious, Dr. Lora Shahine explains why pregnancy can act like an early stress test for the heart. She breaks down chronic hypertension, gestational hypertension, and preeclampsia, reviews common risk factors, and shares what research reveals about the connection between hypertensive disorders of pregnancy and future cardiovascular disease. Dr. Shahine also offers practical ways to advocate for better postpartum care, including sharing your pregnancy history with every healthcare provider, getting regular cardiovascular screenings, supporting heart health through nutrition, exercise, sleep, and stress management, and making your own long-term wellness a priority. In this episode you'll hear: [1:22] Why Preeclampsia Matters [2:50] Hypertension Types Explained [4:28] Risk Factors for Hypertension [5:22] Research Links to Heart Disease [7:30] Postpartum Care Gaps [8:48] Advocacy and Prevention Tips Dr. Shahine's Weekly Newsletter on Fertility News and Recommendations Follow @drlorashahine Instagram | YouTube | Tiktok | Her Books Join the Learn at Pinnacle app to earn FREE CE Credit for listening to this episode! This episode was produced by Audiotocracy Podcast Production.
Do fertility medications increase the risk of breast cancer? Could IVF raise the chances of ovarian or uterine cancer later in life? And how can you separate scientific fertility research from fear-provoking headlines? In this episode of Brave & Curious, Dr. Lora Shahine examines why this fear exists and explores what decades of research actually reveal about fertility medications, IVF, and cancer risk. She explains why this topic is difficult to study, including the need to distinguish the effects of fertility treatment from underlying infertility diagnoses such as endometriosis, PCOS/PMOS, anovulation, and never having carried a pregnancy. Dr. Shahine also discusses the important nuance around prolonged Clomid use, the role of personal risk factors and routine cancer screening, and why patients deserve to make fertility treatment decisions based on evidence rather than fear. In this episode you'll hear: [1:32] A Common Question: Do fertility medications increase my risk of breast cancer? [2:27] Why Research Is Hard [4:44] Breast Cancer Evidence [5:50] Key Study Highlights [9:27] Clomid Cycle Nuance [10:05] Other Cancer Risks (Uterine Cancer, Ovarian Cancer) [12:46] Takeaways And Screening Dr. Shahine's Weekly Newsletter on Fertility News and Recommendations Follow @drlorashahine Instagram | YouTube | Tiktok | Her Books Join the Learn at Pinnacle app to earn FREE CE Credit for listening to this episode! This episode was produced by Audiotocracy Podcast Production.
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