
Ep. 21 Current HFpEF Treatments: Clinical Pearls & Progress with Dr. Jessica Huston
BackTable CardiologyShow Notes
If your New Year’s resolution involves learning more about current practice guidelines and emerging research on Heart Failure with Preserved Ejection Fraction (HFpEF), you’re in the right place! In this episode of the BackTable Cardiology Podcast, host Dr. Hady Lichaa welcomes heart failure specialist Dr. Jessica Huston to provide a practical update on managing heart failure with preserved ejection fraction (HFpEF).
---
SYNPOSIS
Dr. Huston and Dr. Lichaa discuss the complexity of diagnosing HFpEF, differences between HFpEF and diastolic heart failure, phenotypes within HFpEF, and treatment strategies, including the use of aldosterone blockers, SGLT-2 inhibitors, and GLP-1 agonists. Dr. Huston emphasizes the importance of phenotyping patients for accurate diagnosis and treatment, and discusses the potential of future therapies and devices. Their conversation also covers the role of inflammation, metabolic syndrome, and the challenges faced in managing fluid balance and hypertension in HFpEF patients.
---
TIMESTAMPS
00:00 - Introduction02:20 - Understanding HFpEF05:23 - Phenotypes and Treatment Approaches06:29 - Metabolic Syndrome and HFpEF09:17 - Emerging Treatments and Clinical Trials11:36 - Medication Strategies and Challenges24:51 - Diuretics and Their Limitations31:35 - Advanced Diuretic Strategies35:37 - Hemodynamic Measurements and Their Implications40:02 - Coronary Disease and HFpEF42:52 - Future Directions in Heart Failure Treatment45:45 - Device Therapies and Patient Management49:39 - Concluding Thoughts and Future Prospects
---
RESOURCES
Dr. Jessica Huston Provider Profilehttps://healthcare.ascension.org/find-care/provider/1073874616/jessica-huston
Dr. Hady Lichaa Provider Profilehttps://healthcare.ascension.org/find-care/provider/1336267533/hady-lichaa
The SUMMIT Trialhttps://pubmed.ncbi.nlm.nih.gov/39555826/
The TOPCAT Trialhttps://pubmed.ncbi.nlm.nih.gov/24716680/
The FINEARTS Trialhttps://pubmed.ncbi.nlm.nih.gov/39225278/
The CADENCE Trialhttps://www.clinicaltrials.gov/study/NCT04945460
More from BackTable Cardiology
Drug-coated balloons and a head-to-head trial against lithotripsy have put cutting and scoring balloons back at the center of complex percutaneous coronary intervention (PCI). On this episode of BackTable Cardiology, Dr. Nyal Borges interviews Dr. Ziad Ali, director of the DeMatteis Cardiovascular Institute, for an in-depth look at the mechanics, selection, and technique behind cutting and scoring balloons in complex PCI. They cover how these devices create a controlled dissection in fibrolipidic plaque, why they only fracture calcium that sits right at the lumen, and how lesion type and imaging should guide the choice between a conventional balloon, a specialty balloon and intravascular lithotripsy.
What does it actually take to open a chronically occluded pulmonary artery without pushing the patient into reperfusion pulmonary edema? On this episode of BackTable Cardiology, Dr. Hady Lichaa interviews Dr. Riyaz Bashir, interventional cardiologist and vascular medicine specialist at Mayo Clinic in Jacksonville, about the real-world, table-side technique of balloon pulmonary angioplasty for chronic thromboembolic pulmonary hypertension (CTEPH). They walk through vascular access, telescoping sheath setup, right heart catheterization, pressure wire guidance, balloon sizing, and step-by-step planning for each lobe and lesion.
When your questions in cardiology go beyond the bedside and into healthcare innovation and transformation, is an executive MBA your next step? On this episode of BackTable Cardiology, Dr. Ankit Patel interviews Dr. Abdulla A. Damluji of the Cleveland Clinic about his journey from clinical cardiology to business school, and how an MBA empowered him to drive real change in healthcare. Dr. Damluji shares how business education gave him the tools to lead new programs, challenge the financial assumptions behind emerging technologies, and build a cardiovascular center focused on aging.
When a coronary lesion won’t open at conventional pressures, what can an ultra-high pressure balloon do differently? On this episode of BackTable Cardiology, host Dr. Hady Lichaa welcomes Dr. Deepak Kapoor, interventional cardiologist at the Medical College of Georgia at Augusta University, to discuss the science, safety, and real-world applications of ultra-high pressure (UHP) balloons in calcified coronary intervention. Dr. Kapoor walks through the evolution of balloon design, the main scenarios where UHP balloons are most useful, and the technical details that set these devices apart from standard non-compliant balloons and other calcium modification tools.
As new guidelines redefine risk stratification for pulmonary embolism (PE), emerging technologies are also changing what it means to achieve procedural success. On this episode of the BackTable Podcast, interventional radiologist Dr. Julie Bulman (BIDMC) and interventional cardiologist Dr. Jay Giri (Penn Medicine) join host Dr. Chris Beck to discuss the evolving frameworks and technologies redefining standards for catheter-directed treatment of intermediate- and high-risk PE. They discuss the role of multidisciplinary PERT teams, patient selection, the impact of new thrombectomy devices, and why autologous blood return is a growing consideration for procedural success.