AMA 05 - Creatine, Plant Protein, Collagen, Fiber, GLP1s and More

In the latest episode of his Overrated/Underrated series, Dr. Layne Norton ranks the habits, markers, and gadgets the longevity and biohacker crowd won’t stop talking about. No hype. No bro-science. Just what the data actually says about what predicts a longer life, and what has been oversold as a hack. Topics covered: VO2 max, grip strength, cold plunges, sauna, sleep trackers, muscle mass, fasting, biological age tests, and more! Tune in for evidence-based analysis and practical tips on what actually moves the needle for better health and longevity. #LayneNorton #Biolayne #Longevity #Biohacking

Detoxes. Seed oils. Cortisol making you fat. Artificial sweeteners causing weight gain. Insulin as the root of obesity. Hormones as the master switch for fat loss. These ideas keep spreading — even among smart, educated people who should know better. In this episode, Dr. Layne Norton explains why. This is not just another myth-busting list. It’s a breakdown of the psychology, incentives, and media dynamics that make fitness misinformation so sticky. Layne covers why the human brain was not built for science, why anecdotes beat statistics, why fear sells better than nuance, how algorithms reward certainty and outrage, and why intelligence does not protect you from bias. You’ll also get a practical toolkit for evaluating claims: what questions to ask, which red flags matter, how the hierarchy of evidence actually works, and why the “big rocks” of health still outperform the latest viral villain. If you’ve ever wondered why bad fitness ideas travel faster than good evidence, this episode is the map. #LayneNorton #FitnessMisinformation #EvidenceBasedFitness #NutritionScience #Biolayne #SeedOils #ArtificialSweeteners #CriticalThinking #HealthMyths #DrLayneNortonPodcast

In this listener Q&A, Dr. Layne Norton answers your most-asked questions on training, fat loss, genetics, recovery, and how to cut through the noise — with his kitten Wheezy as co-host. Topics covered in this episode: • Training to failure — is it more important for advanced lifters than beginners? • Muscle confusion — why constantly changing exercises creates the illusion of progress (and how much variety is actually useful) • Muscle mass and longevity — is there a point where more muscle stops helping, and why extreme muscularity can look like a U-shaped curve • “I barely eat anything but I’m not losing weight” — why feelings aren’t data, food volume vs calorie density, and why one week of tracking changes everything • Ultra-processed foods — do they cause more fat gain than minimally processed foods when calories are matched? • Metabolic adaptation — how reversible is it, what’s transient vs what’s tied to lost lean mass, and what happens if you stay at the new body weight • How to know who to trust — look for nuance, people who change their minds, logical consistency, and those who haven’t made a diet their identity • Smartwatch recovery scores & HRV — why you should not change your training based on a single day’s number • “Do I have bad genetics?” — Layne’s 10-year answer, chicken-leg-to-world-record-squat story, and the motto “let’s find out” • What Layne loves (and hates) most about his job And more! Whether you’re stuck on fat loss, second-guessing your program, or tired of conflicting advice, this episode gives practical, no-BS takeaways you can use. #BioLayne #LayneNorton #QandA #AMA #EvidenceBasedNutrition #TrainingToFailure #MetabolicAdaptation #FatLoss #MuscleBuilding #Genetics #HRV

In the second installment of the Overrated/Underrated series, Dr. Layne Norton ranks the most talked-about muscle-building strategies as overrated, underrated, or properly rated — based purely on the evidence. No hype. No bro-science. Just what the data actually says about what builds muscle, what doesn’t, and what’s been oversold. Layne covers training intensity, proximity to failure, volume, rep ranges, range of motion, exercise selection, muscle confusion, protein timing, post-workout nutrition, and more! He also explains why he recently changed his mind on calorie surplus, why most people are not training as close to failure as they think, and why stretch/lengthened-position tension matters more than most lifters realize. Whether you’re a coach, athlete, or just trying to build muscle efficiently, this episode cuts through the noise so you can stop wasting time on the overrated stuff and double down on what actually moves the needle. #musclebuilding #hypertrophy #evidencedbasedfitness #DrLayneNorton #Biolayne

In this episode of the Dr. Layne Norton Podcast, Layne sits down with renowned researcher and ketogenic diet expert Dr. Dominic D’Agostino to dive deep into the science of the ketogenic diet. Professor Dominic D’Agostino (University of South Florida Morsani College of Medicine / Institute for Human and Machine Cognition) is one of the leading voices on nutritional ketosis, exogenous ketones, and metabolic therapies. Together, they unpack what the research actually shows about keto – beyond the hype and social media claims. They cover the mechanisms of ketosis, potential therapeutic applications (including epilepsy, metabolic health, neurological conditions, and ongoing research areas like cancer support), practical considerations for implementing a well-designed ketogenic approach, common misconceptions, protein and micronutrient needs, exogenous ketones, and how keto stacks up for fat loss, performance, and long-term adherence compared to other dietary strategies. Expect an evidence-based, no-BS conversation that prioritizes data over dogma. #KetogenicDiet #Keto #DominicDAgostino #LayneNorton #NutritionScience #MetabolicHealth #EvidenceBasedNutrition #DrLayneNortonPodcast