Summary
Concerns arise regarding a new World Health Organization initiative aimed at combating online medical misinformation, which may impact independent content creators. The WHO collaborates with social media platforms to establish guidelines for reporting misinformation, but the implications for non-affiliated channels remain uncertain. The speaker expresses discomfort about how this initiative could affect their ability to produce educational content, especially given their extensive background in healthcare education.
Additionally, the discussion highlights potential conflicts of interest within regulatory agencies due to their funding sources. A report from the British Medical Journal reveals that a significant portion of budgets for agencies like the FDA and the European Medicines Agency comes from the pharmaceutical industry they regulate. This raises questions about the objectivity of these organizations in determining health information. The speaker urges listeners to consider the implications of such funding on the integrity of health information dissemination and encourages them to engage with their representatives on these issues.
Show Notes
WHO and YTUploaded 07-11-22https://www.who.int/teams/digital-health-and-innovation/digital-channels/combatting-misinformation-onlineWHO works with social media policy departments to ensure company policy and guidelines for content providers are fit for purpose.John’s e [email protected]https://www.who.int/campaigns/connecting-the-world-to-combat-coronavirus/how-to-report-misinformation-onlineWHO provide a helpful guide on how to report misinformation onlineInaccurate information spreads widely and at speed, making it more difficult for the public to identify verified facts and advice from trusted sources, such as their local health authority or WHO.https://support.google.com/youtube/answer/9795167?hl=enAs a starting point in the UK, only NHS organisations are being invited to self-certify against the NHS Standard for Creating Health Content. By completing the self-certification process, an NHS organisation channel will be eligible for information panels indicating NHS credibility. From FDA to MHRA: are drug regulators for hire?https://www.bmj.com/content/377/bmj.o1538.fullRegulatory agencies, large proportions of their budgets,funded by the industry they are sworn to regulateUS Food and Drug Administration (FDA)1992, Prescription Drug User Fee Act, allowing industry to fund the US Food and Drug Administration (FDA) directly through “user fees” Net PDUFA fees collected$29m in 1993$884m in 2016 (65% of budget)FDA, 9 out of 10 of its past commissioners between 2006 and 2019 went on to secure roles linked with pharmaceutical companiesEuropean Medicines Agency (EMA)Industry fees funded 20% European Medicines Agency (EMA), in 1995By 2010, 75%Today, 89%Medicines and Healthcare Products Regulatory Agency (MHRA)86% of funding from Pharmaceutical IndustryAustraliahttps://www.tga.gov.auProportion of TGA budget derived from industry, 96%WHO fundinghttps://app.powerbi.com/view?r=eyJrIjoiNzNmNTRkMWEtNmZjMS00NzdjLWEyMDYtYWExYzA4NzVhZGQwIiwidCI6ImY2MTBjMGI3LWJkMjQtNGIzOS04MTBiLTNkYzI4MGFmYjU5MCIsImMiOjh9https://www.weforum.org/agenda/2020/04/who-funds-world-health-organization-un-coronavirus-pandemic-covid-trump/The second-largest funder is the Bill and Melinda Gates Foundation, which provides 9.8% of the WHO's fundsAppendixhttps://genius.com/George-orwell-nineteen-eighty-four-appendix-the-principles-of-newspeak-annotatedhttps://www.orwell.ru/library/novels/1984/english/en_appIt was expected that Newspeak would have finally superseded Oldspeak (or Standard English, as we should call it) by about the year 2050The purpose of Newspeak was not only to provide a medium of expression for the world-view and mental habits proper to the devotees of Ingsoc, but to make all other modes of thought impossible.The C vocabulary was supplementary to the others and consisted entirely of scientific and technical terms. These resembled the scientific terms in use today, and were constructed from the same roots, but the usual care was taken to define them rigidly and strip them of undesirable meanings.War is peace, freedom is slavery, ignorance is strengthNext Monday, 14th November, evidence based medicine confrencehttps://www.eventbrite.co.uk/e/has-big-pharma-hijacked-evidence-based-medicine-tickets-444525075467 Learn more about your ad choices. Visit megaphone.fm/adchoices Learn more about your ad choices. Visit megaphone.fm/adchoices
More from Dr. John Campbell
Serious Adverse Events Uploaded 02-06-25https://www.fda.gov/media/186738/download?attachmentMNEXSPIKE groupSerious adverse events were reported by 2.7% of participants (n=156) Comparator vaccineSerious adverse events were reported by and 2.6% of participants (n=151)(median follow-up of 8.8 months).https://cardiovascular-research-and-innovation.reseaprojournals.com/archive_files/Myocarditis%20after%20SARS-CoV-2%20infection%20and%20COVID-19%20vaccination%20Epidemiology,%20outcomes,%20and%20new%20perspectives.pdf https://investors.modernatx.com/news/news-details/2025/Moderna-Receives-U-S--FDA-Approval-for-COVID-19-Vaccine-mNEXSPIKE/default.aspxhttps://www.fda.gov/vaccines-blood-biologics/mnexspikeTargeted approach against the JN.1 variantParticipants received either mRNA-1283 or mRNA-1273. mRNA-1283 showed a 9.3% higher relative vaccine efficacy (rVE) compared to mRNA-1273 in individuals aged 12 years and older, a 13.5% higher rVE in adults aged 65 and older.https://clinicaltrials.gov/study/NCT05815498https://ctv.veeva.com/study/a-study-of-mrna-1283222-injection-compared-with-mrna-1273222-injection-in-participants-12-years-ohttps://ctv.veeva.comCONTRAINDICATIONS Do not administer MNEXSPIKE to individuals with a known history of severe allergic reactionMyocarditis and Pericarditis, increased risks of myocarditis and pericarditis, risk has been highest in males 12 years through 24 years of age. Onset of symptoms typically in the first week following vaccination Although some individuals with myocarditis and/or pericarditis following administration of mRNA COVID-19 vaccines have required intensive care support, available data suggest that individuals typically have resolution of symptoms within a few days with conservative management.In hospitalized patients who had been diagnosed with COVID-19 vaccine-associated myocarditis,Most of these patients had received a two-dose primary series of an mRNA COVID-19 vaccine prior to their diagnosis. In this study, https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(24)00388-2/fulltextat a median follow-up of approximately 5 months post-vaccination, persistence of abnormal cardiac magnetic resonance imaging (CMR) findings that are a marker for myocardial injury was common. The clinical and prognostic significance of these CMR findings is not knownInformation is not yet available about potential long-term sequelae of myocarditis or pericarditis following administration of mRNA COVID-19 vaccines. 5.3 Syncope Syncope (fainting) may occur in association with administration of injectable vaccines. 5.4 Altered Immunocompetence Immunocompromised persons, including individuals receiving immunosuppressive therapy, may have a diminished immune response to MNEXSPIKE5.5 Limitations of Vaccine Effectiveness MNEXSPIKE may not protect all vaccine recipients. 6 ADVERSE REACTIONS Most commonly (≥10%) reported adverse reactions following administration of MNEXSPIKE: Learn more about your ad choices. Visit megaphone.fm/adchoices Learn more about your ad choices. Visit megaphone.fm/adchoices
United States to follow. 200,000 new omicron infections per day in the UK now.
Yale researchers recognise post-vaccination syndrome (PVS)Uploaded 25-02-25Press release from Yale, Feb 19, 2025 https://news.yale.edu/2025/02/19/immune-markers-post-vaccination-syndrome-indicate-future-research-directionsImmunological and Antigenic Signatures Associated with Chronic Illnesses after COVID-19 Vaccinationhttps://www.medrxiv.org/content/10.1101/2025.02.18.25322379v1Chronic symptoms that developed a day or two soon after receiving a COVID-19 vaccine,can become more severe in the days that follow, PVS, little-understood, persistent condition, remains unrecognized by medical authorities. Common chronic symptoms of PVSExcessive fatigue (85%)Tingling and numbness (80%)Exercise intolerance (80%)Brain fog (77.5%)Difficulty concentrating or focusing (72.5%)Trouble falling or staying asleep (70%)Neuropathy (70%)Muscle aches (70%)Anxiety (65%)Tinnitus (60%) Burning sensations (57.5%).Getting out of breathPalpitationsHeadacheDizzinessLower quality of life scoresMechanismsVaccine-induced immune responses may be triggering the stimulation of autoreactive lymphocytes.Unregulated stimulation of innate immunity could lead to chronic inflammation. Participants with PVS have a distinct set of autoantibodies.A subset of non-classical monocytes has been shown to harbor S protein in patients with PVSBiodistribution studies on mRNA–LNP platforms in indicate its ability to cross the blood-brain barrier, and the local S expression could result in neurocognitive symptoms.Compared with controlsPVS had reduced circulating memory and effector CD4 T cells,and an increase in TNFα+ CD8 T cells. Serological evidence of recent Epstein-Barr virus (EBV) reactivation, more frequent in PVS. Measured levels of SARS-CoV-2 spike protein Participants with PVS had significantly higher circulating S1 levels compared with the control group (p = 0.01). PVS, (even those without evidence for infection), higher levels of spike protein than controls. Detectable S1 was found in participants' plasma ranging from 26 to 709 days from the most recent known vaccination.“That was surprising, to find spike protein in circulation at such a late time point,”(Some PVS patients didn’t have any measurable spike protein).Autoimmunity, tissue damage, Epstein-Barr Virus (EBV) reactivation, (infectious mononucleosis)https://www.medrxiv.org/content/Immunological and Antigenic Signatures Associated with Chronic Illnesses after1 COVID-19 Vaccination.pdfYale LISTEN study. LISTEN stands for Listen to Immune, Symptom and Treatment Experiences Now.https://medicine.yale.edu/ycci/listen-study/42 LISTEN PVS patients (some never infected)22 who did not report any PVS symptoms after COVID-19 vaccination.“It’s clear that some individuals are experiencing significant challenges after vaccination. Our responsibility as scientists and clinicians is to listen to their experiences, rigorously investigate the underlying causes, and seek ways to help,” Learn more about your ad choices. Visit megaphone.fm/adchoices Learn more about your ad choices. Visit megaphone.fm/adchoices
Long covid seems to be the same as any other post viral syndrome
and the strange case of Chine continuesUploaded 12-04-22USOmicron BA.2Nationally, 3% over last two weeksCases, + 31,000Higher in New York City (cases up 39% in past 2 weeks)Washington, D.C.https://covid.cdc.gov/covid-data-tracker/#new-hospital-admissionsHospital patients down 8.2% past weekCovid-19 Wastewater Monitoring in the U.S.SARS-CoV-2 virus concentration (copies / mL of sewage)https://biobot.io/data/The level of virus in wastewater is a leading indicator, meaning it precedes the change in clinical case counts or hospitalizations.Philadelphiahttps://www.nytimes.com/2022/04/11/us/philadelphia-indoor-mask-mandate.htmlMonday, reinstate indoor mask mandateFirst major U.S. city to do soCheryl Bettigole, health commissionerThis is our chance to get ahead of the pandemicCases, + 142(Omicron wave, + 4,000)knowing that every previous wave of infections has been followed by a wave of hospitalizations, and then a wave of deaths, then it will be too late for many of our residentsWhite House, Dr. Ashish K. JhaWe’ve got to watch this very carefully, But I don’t think this is a moment where we have to be excessively concernedRight now that is showing an uptick, but not showing substantial changes in what we should be doingMayor Eric Adams, New York CityTested positive on SundayDiabeticI feel fine, no fever, no running nose, no aches and painsI would probably have had different outcomes if I was not vaccinated and boostedShanghai China has reported more than 200,000 locally transmitted casesMost mild or asymptomaticOne case, currently categorized as “severe”No deaths reported in the current outbreakUS State departmentNonemergency U.S. consulate, ordered outAmericans should avoid traveling to China, arbitrary enforcement of local laws and Covid-19 related restrictions25 million locked down since 1st AprilSome family separationsLiang Wannian, senior official, China’s National Health CommissionWe cannot let our guard downpeople first, lives firstlying flat is not an option for ChinaOver 60s in China264 million40 million of them unvaccinatedInfections among this group inevitableGuangzhou30 casesPCR testing 18 million Learn more about your ad choices. Visit megaphone.fm/adchoices Learn more about your ad choices. Visit megaphone.fm/adchoices