Show Notes
This episode is brought to you by Solaray
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Dr. Kien Vuu and I talk about cellular energy, estrogen, NAD+ and spermidine in midlife, and how to build more energy today while staying strong and sharp at 80.
Physician and Thrive State author Dr. Kien Vuu breaks down the three parts of one energy system behind midlife fatigue: mitochondria, insulin sensitivity and metabolic flexibility. He explains why falling estrogen hits mitochondrial efficiency, glucose metabolism, muscle and bone at the same moment life demand peaks, why fasting glucose and HbA1c move late, and how he sorts longevity compounds into mapped, emerging and frontier science before deciding whether glutathione, NAD or spermidine earn a place on top of the foundations.
WHAT YOU'LL LEARN
- Why the felt sense of low energy shows up long before fasting glucose or HbA1c move
- What falling estrogen does to mitochondrial efficiency, glucose metabolism and muscle mass at the exact moment life demand peaks
- How to sort any longevity compound into mapped, emerging or frontier science before you spend a penny
- The four questions Dr. Vuu asks before adding a supplement, and why he says you have to earn it first
WHAT YOU'LL LEARN
- Why the felt sense of low energy shows up long before fasting glucose or HbA1c move
- What falling estrogen does to mitochondrial efficiency, glucose metabolism and muscle mass at the exact moment life demand peaks
- How to sort any longevity compound into mapped, emerging or frontier science before you spend a penny
- The four questions Dr. Vuu asks before adding a supplement, and why he says you have to earn it first
TIMESTAMPS
00:00 - Intro: Why Your Energy Drops in Midlife Before Anything Shows on a Blood Test
10:02 - Perimenopause, Estrogen and What Changes at the Cellular Level After 40
16:25 - Epigenetics, the Five Foundations, and How to Judge a Longevity Supplement
25:51 - Glutathione, NAD, NADH and NMN for Oxidative Stress and Cellular Energy
35:09 - Spermidine, Autophagy and the Senescent Cell Frontier
43:04 - Where a Busy Woman in Midlife Should Actually Start
VALUABLE RESOURCES
Dr. Kien Vuu’s website https://kienvuu.com/
Thrive State (Dr. Kien's book), free PDF: https://thrivestatestarter.com
Follow Dr. Kien Vuu on Instagram: https://www.instagram.com/doctorvmd
Listen to Dr. Kien Vuu’s Podcast: https://podcasts.apple.com/ph/podcast/thrive-state-podcast/id1548233524
ABOUT THE GUEST
Dr. Kien Vuu is a physician, human performance and longevity expert, and the author of Thrive State. He hosts the Thrive State podcast and is a brand partner and advisor to Solaray. A former chief of interventional radiology, he burnt out in his mid-30s and developed type 2 diabetes and high blood pressure. That experience drives his mission to help people build energy and longevity through five pillars of health: physical, mental, emotional, social and spiritual.
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