The Peptide Story: Past, Present & Future

Midlife Women & GLP-1s: Why Weight Loss Gets Harder (and How GLP-1s Can Help) Nurse practitioner Sophie Mengele from Turner Medical Arts discusses midlife women’s health and why GLP-1 medications can be especially helpful when weight loss stalls despite healthy habits like walking 10,000 steps, cutting alcohol, and eating well. She explains that changing estrogen levels in midlife can reduce insulin sensitivity and contribute to stubborn fat retention, making weight loss more difficult than it is for men or for women earlier in life. Sophie outlines how GLP-1s can improve insulin sensitivity and curb appetite, reducing constant thoughts about food, and describes GLP-1s as one tool in the toolbox to help midlife women reach their weight and health goals. 00:00 Why GLP1 for menopausal women 00:05 Does This Sound Like You? 00:21 Meet Sophie & Why It's Harder for Midlife Women 00:57 How GLP-1s Help 01:49 Real Patient Stories https://www.turnermedicalarts.com https://www.youtube.com/@thevaginadoctor

The Vagina Doctor Podcast: Consult With Me with Duncan Turner MD & Karen Spaulding Pelvic Floor Health After Birth: Therapy, Kegels, and Non-Surgical Options In this episode, the host Dr. Turner & Karen Spaulding discuss common pelvic floor issues inspired by a new patient with four vaginal births who is also doing pelvic floor therapy. Dr. Turner explains the pelvic floor’s role in supporting abdominal organs and how factors like vaginal delivery, chronic coughing, gravity, and even excessive weightlifting can stretch it, leading to problems such as stress urinary incontinence and prolapse. They cover prevention and treatment options, emphasizing pelvic floor physical therapy to teach patients how to properly engage these muscles, along with supportive treatments like vaginal estrogen, electrical muscle stimulation (including VTone), and energy-based therapies. They note that surgery can help but has complications and is best avoided when possible, and highlight postpartum as an important time to address pelvic floor health. 00:00 Breaking the Silence: The Unseen Crisis of Pelvic Health 00:00 Patient Story & Intro 01:31 Pelvic Floor Anatomy & Causes 04:40 Treatment Options 08:06 Postpartum Focus & Wrap-Up

Duncan Turner MD & Remi Drozd. Lucid Therapeutics’ New Insurance-Covered Ketamine Model, TMS, and the Coming FDA Shift on Psychedelics | Remi Drozd Remi Drozd returns to the Vagina Doctor podcast to explain how Lucid Therapeutics has evolved after treating thousands of patients, shifting from short, expensive out-of-pocket psychedelic integration to an insurance-covered, co-pay model focused on long-term programs and durability. He describes their patient journey: assessment, trauma- and psychedelic-informed coaching, a workbook-based mindfulness practice, and lower-dose continuous nasal ketamine (often weekly early on, then tapered), with the option to add insurance-covered TMS (36 brief treatments) to further neuromodulate mood pathways. Drozd discusses clinic growth to 10 treatment rooms, expanded staffing, and the operational work required for insurance. He also reviews an FDA hearing on broader psychedelic access, Compass Pathways’ planned psilocybin rollout and monitoring/training considerations, plus adjunct offerings like injectable peptides for sleep and stem cell/MU cell IV therapies that are typically not covered by insurance. 00:00 Remi Drozd getting us caught up on all that's Happening at Lucid Therapeutics 00:30 Welcome Back 00:42 Changes at Lucid Therapeutics 04:44 TMS Treatment Explained 06:57 The Patient Journey 10:40 Practice Expansion 14:31 FDA Psychedelic Hearing 18:26 Compass Pathways & Psilocybin 28:52 Provider Training & Experience 29:57 Stem Cells & Peptides 36:25 Closing & Call to Action

The Vagina Doctor Podcast: Botox for Overactive Bladder: How It Works, Risks, and Who It Helps Duncan Turner MD discuss Botox injections as a treatment for overactive bladder and urge incontinence, prompted by a former patient who had excellent results and questions about dosing and injection placement. They explain that Botox is injected into the bladder muscle to reduce overactive contractions, is now FDA approved and generally covered by insurance, and is increasingly used by urologists via cystoscopy, though it can also be done with a transvaginal approach guided by anatomy and ultrasound. They emphasize potential complications, especially urinary retention that may require catheterization and can increase infection risk, so testing such as measuring post-void residual bladder volume is recommended beforehand. Ideal candidates are those with severe urinary frequency or significant nighttime urination that disrupts daily life. 00:00 Introduction 00:05 Consultation Overview 01:04 How Botox Works 02:57 Side Effects & Risks 04:14 Testing & Ideal Patient 05:47 Prevalence & Impact

Midlife Belly Fat Explained: Estrogen, Perimenopause, HRT & GLP-1s Sophie Mengele The Women's Health Edit on The Vagina Doctor Podcast explains why many women struggle to lose stubborn midline belly fat in perimenopause and menopause, emphasizing fluctuating and overall declining estrogen as a key driver. She describes how, starting about two years before the last period, estrogen shifts from rhythmic cycles to spikes and crashes, contributing to increased belly fat storage, reduced satiety signaling, and gradual muscle loss of about 1–1.5% per year. She notes that even with frequent exercise and healthy eating, body shape and metabolism can change, and added belly fat can reduce insulin sensitivity, making blood sugar control harder. Sophie discusses hormone replacement therapy as helpful for symptoms like hot flashes and night sweats and for some muscle and fat effects, but not a complete return to prior body shape, leading some patients to consider combining HRT with a microdose of GLP-1 medications. 00:00 Estrogen & Weight 00:23 Perimenopause Shift 01:19 Muscle Loss Stats 02:16 HRT Reality 03:16 GLP-1 Solution https://www.yutube.com/@thevaginadoctor https://www.turnermedicalarts.com