That Great Business Show

E290 That Great Business Show - 2025 corporation tax jump almost entirely due to single peptide-based hormone - Neil McDonnell, CEO, ISME

That Great Business Show

Show Notes

Welcome to Episode 290 of That Great Business Show.

This is not a comfortable listen. Ireland — the poster child of global success — is quietly sitting on a knife edge. A handful of multinationals are driving the tax take. One peptide. One state in America. One shock away from a very rude awakening.

My guest is Neil McDonnell, CEO of ISME — and he’s not here to play nice. We get into: The dangerous illusion of “paradox of plenty” €340 BILLION sitting idle while SMEs starve Why government knows the risks — and still does nothing The tax system that punishes Irish entrepreneurs but rolls out the red carpet for outsiders And the simple, practical fixes that could change everything — if anyone had the courage This is real business. Press the subscribe button.

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