The Pathology Report

Neoadjuvant paradigm shift in melanoma patient care

The Pathology Report

Show Notes

Thank you to our partner Bristol Myers Squibb (BMS) for their support in producing this podcast episode.

Recent advances in the use of neoadjuvant therapies for melanoma mean that pathologists are now at the forefront of clinical decision-making and patient care.

In this episode of The Pathology Report, host A/Prof Diane Kenwright is joined by anatomical pathologists, Dr Louise Jackett, Dr Robert Rawson and Dr Danielle Vignati to discuss the latest clinical trials and research, with practical approaches to help pathologists navigate this rapidly evolving field.

Key topics include: Immunotherapy and its role in treating high stage melanoma and other cancer streams. How undertaking immunotherapy as a neoadjuvant prior to an intentional resection impacts melanoma patient prognosis and treatment. Post-resection examination and practical approaches to recognising the tumour bed. Accurately calculating the pathological response of the patient to immunotherapy using cut-offs, and the role of pathologists in multidisciplinary care teams. Updated protocols and guidelines and ongoing neoadjuvant research.

With practical insights from leading experts in melanoma research and care, this episode is an excellent resource for pathologists wanting to stay up to date on the latest neoadjuvant advances and optimise patient outcomes.

Episode links Peter MacCallum Cancer Centre Tetzlaff, M T et al. “Pathological assessment of resection specimens after neoadjuvant therapy for metastatic melanoma.” Annals of oncology : official journal of the European Society for Medical Oncology vol. 29,8 (2018): 1861-1868. doi:10.1093/annonc/mdy226

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