Customized care and fertility

US cases still low, but I expect them to riseUploaded 11-04-22https://www.nytimes.com/2022/04/06/briefing/covid-cases-us-omicron-subvariant.html?action=click&pgtype=LegacyCollection&state=default&module=styln-coronavirus&variant=show®ion=BELOW_MAIN_CONTENT&block=storyline_flex_guide_recircDown about 1% as BA.2 has become the dominantOriginal Omicron, so contagious, predictable global spreadMore immunityIn liberal parts of the U.S., vaccination rates highConservative communities, normal life for some time(death rates have been higher)BA.2 has recently become dominant variant in India, South Africa, AfricaAndy Slavitt, former Biden Covid adviserBA.1 has infected 45% of AmericansFewer testsUninsured people now must pay foe testsMany testing clinics have closedJessica Malaty Rivera, Boston Children’s HospitalQuality of current Covid data “abysmal.”Dr. Scott Gottlieb, former F.D.A. commissionerSome parts of the country “dramatically” underreporting casesTrends in Covid hospitalizations lag case trends by about a week(hospitalizations have continued to fall in the U.S.)Best guessU.S. infections will rise soon Learn more about your ad choices. Visit megaphone.fm/adchoices Learn more about your ad choices. Visit megaphone.fm/adchoices

Richer countries ongoing excess deathsUploaded 08-09-23Our world in data, excess mortalityhttps://ourworldindata.org/grapher/excess-mortality-p-scores-average-baseline?country=~BIHOur world in data covid vaccination statushttps://ourworldindata.org/coronavirusOffice for health improvementhttps://app.powerbi.com/view?r=eyJrIjoiYmUwNmFhMjYtNGZhYS00NDk2LWFlMTAtOTg0OGNhNmFiNGM0IiwidCI6ImVlNGUxNDk5LTRhMzUtNGIyZS1hZDQ3LTVmM2NmOWRlODY2NiIsImMiOjh9https://www.ons.gov.uk/peoplepopulationandcommunity/birthsdeathsandmarriages/deaths/bulletins/deathsregisteredweeklyinenglandandwalesprovisional/weekending25august2023Week ending 25 August 2023 (Week 34)England and Wales10,086 deaths203 mentioned novel coronavirus2.0% of all deaths Of the 203 deaths67.0% (136 deaths) recorded as underlying cause of deathDeaths registered in the UK11,522, (4.5% above five-year average) Learn more about your ad choices. Visit megaphone.fm/adchoices Learn more about your ad choices. Visit megaphone.fm/adchoices

DW news, quite rightly and correctly, asked me for clarification on my contention that the virus was likely to have arisen in Africa. We know that a young woman arrived from Egypt who had flown via Turkey into Belgium landing on the 11th of November.Uploaded 27-11-21We also we also know that she became symptomatic and tested positive for the omicron variant on the 22nd of November.It is possible that this young woman had a long incubation period of 11 days or more, but this is somewhat improbable.This clearly leaves open the possibility that she contracted the virus within Belgium, between the 11th and 22nd of November.It is therefore within the bounds of possibility that she originally contracted this virus in Egypt, or on the flight from Egypt to Turkey, or the flight from Turkey to Belgium, or in Belgium.This is what we know so far and of course it is important not to over extrapolate from the facts at our disposal. Learn more about your ad choices. Visit megaphone.fm/adchoices Learn more about your ad choices. Visit megaphone.fm/adchoices

European Centre for Disease Prevention and Control BA.4 and BA.5Uploaded 20-05-22https://www.ecdc.europa.eu/en/covid-19/variants-concernhttps://www.ecdc.europa.eu/en/news-events/epidemiological-update-sars-cov-2-omicron-sub-lineages-ba4-and-ba512th May, ECDC reclassified omicron subvariants, BA.4 and BA.5 as VOCsFirst detected in South Africa in January and February 2022Now dominant in SABoth lineages contain L452R, F486V, and R493Q in the spike receptor binding domainSignificant change in antigenic properties of BA.4 and BA.5 compared to BA.1 and BA.2PortugalBA.5, increasing trend in variant proportionsWith increase in case numbers and test positivity ratePortuguese National Institute of HealthBA.5 already accounted for ~37% of positive cases as of 8 MayDaily growth advantage for BA.5 over BA.2 is 13%(SA estimated 12% daily growth advantage)BA.5 will become the dominant variant in Portugal by 22 May 2022Growth advantage for BA.4 and BA.5Evade immune protection induced by prior infection and/or vaccination, particularly if this has waned over timeBA.4 and BA.5 are capable of escaping immune protection induced by infection with BA.1No indication of any change in severity for BA.4/BA.5 compared to previous Omicron lineages.These variants could cause a significant overall increase in cases in EuropeIf COVID-19 case numbers increase substantially, some level of increased hospitalCountries should have plans in place for the rapid deployment of booster doses in these population groups.Our world in datahttps://ourworldindata.org/coronavirusUS variant nowcasthttps://covid.cdc.gov/covid-data-tracker/#variant-proportionsSouth Africahttps://www.nicd.ac.za/diseases-a-z-index/disease-index-covid-19/surveillance-reports/daily-hospital-surveillance-datcov-report/SARS-CoV-2 variants of concern and variants under investigation in England Technical briefing 41 https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/1073698/Technical-Briefing-41.pdfV-22APR-03 (Omicron sub-lineage BA.4) and V-22APR-04 (Omicron sub-lineage BA.5) As of 3 May 2022BA.4 40 genomesBA.5 19 genomes Monkeypox updatehttps://pubmed.ncbi.nlm.nih.gov/23142251/Massachusetts public health officials confirm case of monkeypoxhttps://www.mass.gov/news/massachusetts-public-health-officials-confirm-case-of-monkeypoxAn adult male with recent travel to CanadaAustraliahttps://www.theguardian.com/australia-news/2022/may/20/australias-first-probable-case-of-monkeypox-virus-identified-in-nswVictoria, man 30s traveller from UKNSW, man 40s traveller from EuropeJennifer McQuiston at the US Centers for Disease Control and Preventionhttps://www.statnews.com/2022/05/18/spain-portugal-report-monkeypox-cases-raising-specter-of-wider-outbreak/?utm_source=Nature+Briefing&utm_campaign=7a51987021-briefing-dy-20220519&utm_medium=email&utm_term=0_c9dfd39373-7a51987021-44762053We’re seeing this expansion of confirmed and suspect cases globallyWe have a sense that no one has their arms around this to know how large and expansive it might beMaria Van Kerkhove, emerging diseases and zoonoses unit, World Health OrganizationPositive cases identified in the U.K., Portugal, and Spain (Sweden)And we expect there will be others Learn more about your ad choices. Visit megaphone.fm/adchoices Learn more about your ad choices. Visit megaphone.fm/adchoices

A Hearing with Dr. Anthony Fauci https://oversight.house.gov/hearing/a-hearing-with-dr-anthony-fauci/ Learn more about your ad choices. Visit megaphone.fm/adchoices