Show Notes
In this episode, I'm breaking down sections 4.2.3 through 4.2.10 of the dense ACC/AHA dyslipidemia guidelines so you don't have to. We'll cut through the noise on the new PREVENT equations, risk enhancers, imaging, and algorithms for primary and secondary prevention. Let's get you equipped to handle these complex lipid management decisions in the clinic.
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CHAPTERS: 00:00 - Intro 00:25 - Individualized Risk-Benefit Discussions 02:24 - The New PREVENT ASCVD Equations Explained 04:29 - Understanding New Risk Thresholds 05:32 - The Math Behind the 3% Treatment Threshold 09:28 - Risk Enhancers and Personalizing Risk 11:21 - Reproductive Age Risk Markers 12:15 - Polygenic Risk Scores 13:12 - Selective Imaging: CAC and Coronary CT 15:16 - Treating Incidental Plaque 15:58 - The Core Primary Prevention Algorithm 19:26 - Severe Hypercholesterolemia (LDL > 190) 21:58 - Diabetes and Lipid Management 23:15 - Residual Risk and Omega-3s 23:37 - Secondary Prevention Targets 26:46 - Special Populations: Children and Young Adults 28:04 - Older Adults and Deprescribing 28:54 - Pregnancy and Lactation 29:55 - HIV, CKD, and Inflammatory Diseases 31:14 - Heart Failure and Cancer Survivors 32:05 - Managing Hypertriglyceridemia 34:18 - Lipoprotein(a) as a Risk Enhancer
SELECTED REFERENCES: https://www.ahajournals.org/doi/10.1161/CIR.0000000000001423
*Disclaimer* This podcast is for entertainment, education, and informational purposes only. The topics discussed should not solely be used to diagnose, treat , or prevent any condition. The information presented here was created with an evidence based approach, but you please keep in mind that science is always changing and at the time of listening to this there may some new data that makes this information incomplete or inaccurate. Always seek the advice of your personal physician or qualified health care provider for questions regarding any medical condition.
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