BIOACTIVE

How Animals Medicate with Dr. Jaap De Roode

BIOACTIVE

Show Notes

In this conversation, host Dr. Riley Kirk and guest Dr. Jaap De Roode discuss the fascinating field of zoo pharmacognosy, exploring how animals medicate themselves using natural substances. He shares insights from his research on monarch butterflies and honeybees, highlighting the role of toxic compounds and fungi in animal health. The discussion also touches on the implications for agriculture, the importance of biodiversity, and the potential for learning from animal behaviors in medicine. Dr. De Roode emphasizes the need for more research in this area and the significance of maintaining natural ecosystems for the health of both animals and humans.

Key Takeaways

Zoo pharmacognosy is the study of how animals medicate themselves.

Monarch butterflies use toxic milkweed compounds to combat parasites.

Honeybees may use fungi to treat infections in their colonies.

Animal medication can be a learned behavior or instinctual response.

Diversity in diet is crucial for animal health and resilience.

Propolis serves as both a cement and a medicinal substance for bees.

Observational studies provide insights into animal medication behaviors.

Animals can change their behavior based on their health needs.

Research on animal medication can inform agricultural practices.

Understanding animal medication can lead to new discoveries in human medicine.

Chapters

00:00 Introduction to Zoo Pharmacognosy

04:08 Research Focus: Monarch Butterflies and Honeybees

10:58 Defining Animal Medication vs. Self-Medication

14:59 Examples of Animal Medication in Nature

18:20 Chimpanzees and Traditional Healing

24:38 Learning and Sharing Medicinal Knowledge in Animals

26:14 The Fascinating World of Animal Self-Medication

28:53 Agricultural Practices and Animal Health

32:38 The Importance of Choice and Diversity in Animal Diets

33:37 Studying Animal Behavior and Medicating Practices

35:56 Recreational Use of Plants by Animals

40:56 Addressing Animal Anxiety and Depression

43:52 Natural Products in Animal Medicating

46:21 Evolution of Medicating Behaviors in Animals

48:21 Cannabis and Animal Self-Medication

51:31 Researching Fungi and Bees

55:20 Insights from 'Doctors by Nature'

Thank you to our sponsor for this episode GAVITA: For over 40 years, Gavita has been the trusted name in horticultural lighting, setting the benchmark for performance, reliability, and innovation. https://gavita.com/category/led-grow-lights/ IG: @gavitanorthamerica

Follow Dr. De Roode’s research:

https://biology.emory.edu/people/bios/faculty/de-roode-jaap.html

Follow Dr. De Roode on IG and LinkedIn

IG @jaapderoode

LI: https://www.linkedin.com/in/jaap-de-roode-04a6a6237/

Read or listen to Doctors by Nature

https://www.amazon.com/Doctors-Nature-Other-Animals-Themselves/dp/069123924X

Check out my book Reefer Wellness!

⁠⁠⁠https://www.amazon.com/Reefer-Wellness-Understanding-Cannabis-Medicine/dp/0593847156⁠⁠⁠

✨ Want Exclusive Content?

Join the Bioactive Patreon community for as little as $1/month to ask guests your burning questions, access exclusive content, and connect with Dr. Kirk one-on-one.⁠⁠⁠ www.Patreon.com/Cannabichem⁠⁠⁠

🔔 Don’t forget to like, subscribe, and hit the notification bell for more expert insights into cannabis science, plant biology, and more!

Keep up with Dr. Riley Kirk:

https://www.bioactivepodcast.com/

https://www.youtube.com/@cannabichem

https://instagram.com/cannabichem

⁠⁠⁠https://www.appliedpharmacognosy.org/⁠⁠⁠

Learn more about your ad choices. Visit megaphone.fm/adchoices

More from BIOACTIVE

Oct 16, 2026

What are cannabis terpenes, how do they influence aroma and consumer experiences, and what do we know about their safety? On this episode of the Bioactive Podcast, Dr. Riley Kirk sits down with Dr. Shawna Vreeke, PhD, DABT, Head of Toxicology at True Terpenes, to explore the science of cannabis terpenes, terpene chemistry, cannabinoid interactions, and consumer safety. With a PhD in Chemistry focused on toxin formation in vape device aerosols and expertise in toxicology risk assessment, Shawna shares insights into what current research tells us about terpenes and where important questions remain unanswered.

Oct 3, 2026

Dr. Riley Kirk welcomes Dr. Miyabe Shields for a deep dive into cannabis real-world data, cannabis consumption patterns, dosing, neurodivergent cannabis use, and the Endocannabinoid System (ECS). As co-founders of the Network of Applied Pharmacognosy (NAP), Riley and Miyabe discuss the newly accessible Real Data Project, including what large-scale consumer data can reveal about how people actually use cannabis in their everyday lives.

Sep 18, 2026

What if carbon is one of the most overlooked inputs in plant nutrition? In this episode of the Bioactive Podcast, Dr. Riley Kirk sits down with Nik Nikolayev, CEO of Rooted Leaf Agritech, to explore the science of carbon-based fertilizers, plant nutrition, biostimulants, organic acids, and the chemistry behind plant growth, yield, and quality.

Sep 4, 2026

Dr. Riley Kirk has Dr. Denise Valenti on the podcast to discuss cannabis and driving, cannabis impairment, THC testing, and the challenges of determining whether someone is actually too impaired to drive. They explore why THC levels in the body do not necessarily correspond to impairment and how cannabis can affect vision, peripheral vision, contrast sensitivity, eye movement, balance, and pupil response.

Aug 25, 2026

In this episode of the Bioactive Podcast, Dr. Riley Kirk sits down with Dr. Rick Pescatore, board-certified emergency physician, Editor-in-Chief of Emergency Medicine News, and founder of BellyMD, for a fascinating deep dive into the gut-brain connection and what it means for cannabis users and patients dealing with unexplained digestive symptoms.

See all episodes →