Show Notes
Dr. Dominic D’Agostino is a scientist and associate professor at the University of South Florida, internationally known for his research on ketosis, metabolic health, and human performance. His work explores the therapeutic and performance benefits of ketogenic diets, fasting, and metabolic therapies, including applications in cancer, neurological disorders, and extreme environments. Dr. D’Agostino has advised elite military units, NASA-affiliated research programs, and professional athletes. He is widely respected for translating cutting-edge metabolic science into practical strategies for health and resilience.
In our conversation we discuss: (0:00) What is the ketogenic diet overview (2:52) How carbs versus keto affect the body (5:44) Why should someone try keto (9:45) Mental focus benefits of ketosis (14:48) Cyclical versus continuous ketogenic dieting (22:56) Keto fat intake and cardiovascular risk (32:40) Low-carb versus strict keto risks (37:35) Carnivore diet versus ketogenic diet (43:22) Ancestral eating and adding berries (48:11) Best timing for carbs on keto (52:35) How beginners should start keto (57:12) Managing keto flu and side effects (1:01:10) Ketosis effects on sleep quality (1:07:48) Melatonin use and long-term safety (1:13:02) Quality of life versus strict dieting (1:19:14) Where to learn more about keto research
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TRIGGER WARNING: Discussions of suicide and depressionIf anyone watching is personally struggling, the 988 Suicide & Crisis Lifeline (call or text 988 in the US) is always available.
Christopher Gardner, PhD, is a nutrition scientist and Professor of Medicine at Stanford University, where he has led more than 20 large-scale randomized clinical trials comparing diets like keto, vegan, low-fat, and low-carb. He's the past chair of the American Heart Association's Nutrition Committee and the author of the upcoming book Food Sense, which argues there's far more scientific consensus about what to eat than the internet's diet wars would suggest. In this episode, we discuss: