#139 - Meet The Greatest Ibogaine Psychedelic Scientist You’ve Never Heard Of

Download the most scientifically rigorous nutrition app MacroFactor! Use code GIANTS for a 2 week FREE trial: https://onelink.to/giants Get Manta Sleep Mask: https://bit.ly/4ilzfBL and Code GIANTSMANTA10Want a full breakdown of your own conscious inner experience? Join the Giant's Shoulder community: https://www.skool.com/the-giants-shoulder-6526/about Dalibor Sames is the chemist who reverse-engineered ibogaine into a version that appears to erase heroin addiction in a single dose, without the cardiac risk that can kill people on the original drug. He also took his own medicine — and says he watched the molecule's exact 3D structure rotate in front of him for 36 hours straight.Expect to learn why ibogaine breaks every rule of classical pharmacology, what "matrix pharmacology" means and why it's heresy to a one-drug-one-target industry, how editing a single atom deletes ibogaine's fatal heart risk, why a common antidepressant turned out to be a secret opioid for thirty years, what it's like to watch a molecule's structure appear during a 36-hour flood dose, why ibogaine seems to erase interest in alcohol overnight, whether the "DMT block" phenomenon researchers describe is real, and much more… Timestamps0:00:00 Trailer0:02:39 Meet the Chemist Who Fell for a Molecule's Shape 0:04:13 The Dogma That the Adult Brain Can't Heal0:09:00 Why Synapses Might Explain Every Brain Disorder0:10:28 Reverse-Engineering Nature's Own Drugs 0:16:44 The Paper That Changed Everything About Addiction 0:20:01 Why Ibogaine Breaks Every Rule of Pharmacology 0:33:08 The Weakest Drug That Works the Strongest 0:38:21 The Traffic Jam That Explains Matrix Pharmacology 0:44:18 A Human Genome Project — For One Molecule 0:47:48 Deciding to Take Ibogaine Himself 0:50:02 Inside a 36-Hour Flood Dose 0:54:38 The Chapter Called "Treatment" 0:56:26 Ibogaine Shows Him the Future of Design 1:00:01 Seeing Ibogaine's 3D Molecular Structure 1:03:14 High-Fiving a Molecule1:06:47 "This Is a Computational Technology" 1:16:36 The Simulation So Real It Panicked Him 1:24:26 Did He Earn This Experience? 1:30:56 Six Months Later — What Actually Changed 1:36:01 Did This Change His View of Consciousness?...... Email for sponsorship enquiries: [email protected] GS Episodes Mentioned Andrew Gallimore — No.1 DMT Neurobiologist: Alien Worlds, DMT Entity Encounters, Attractor States and Consciousness: https://www.youtube.com/watch?v=USgWrxEFWDA David Luke — Meet the Professor of Paranormal Consciousness - DMT Entities, Telepathy Tapes & OBE's: https://www.youtube.com/watch?v=qLKD1gt1X5oGuest LinksColumbia Chemistry faculty page: https://www.chem.columbia.edu/content/dalibor-sames Sames Lab: https://www.samesgroup.org/professor-dalibor-sames Gilgamesh Pharmaceuticals: https://www.gilgameshpharmaceutical.com/ Oxa-Iboga paper (Nature Communications, 2024): https://doi.org/10.1038/s41467-024-51856-y Beond Ibogaine Clinic (where he took ibogaine): https://beondibogaine.com