Show Notes
Want to get even more jacked? Grab the RP Hypertrophy App for your training, and maximize your gym efforts with the RP Diet Coach App to nail your nutrition. Guest Links Dr. Eric Trexler's Links: Instagram: @trexlerfitness ResearchGate: Eric Trexler publications Research review: MASS Research Review Timestamps 00:00 Weight-loss non-responders and the laws of thermodynamics 03:22 Rare medical conditions and extreme hunger 06:34 Hunger genetics, GLP-1s, and learning empathy 12:15 Lipedema and regionally resistant fat 21:48 PCOS, hypothyroidism, and what they do to metabolism 31:08 Three reasons weight loss can feel impossible 36:34 Tracking errors and the classic underreporting study 46:08 Food-label and restaurant-calorie errors 50:33 Controlled diet research and metabolic adaptation 58:39 Support, adherence, and why consistently showing up works 01:03:14 GLP-1s, side effects, and personalized dosing 01:10:45 Aging, activity, stress, and the myth of the 40-year-old metabolism
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Want to get even more jacked? Grab the RP Hypertrophy App for your training, and maximize your gym efforts with the RP Diet Coach App to nail your nutrition.
Nick Shaw and Dr. Eric Trexler discuss oral GLP-1 options, how the newer drugs compare, and practical questions about dosing, side effects, muscle retention, and possible benefits beyond weight loss. They also examine research on weight regain after stopping treatment, the cost of long-term access, and how these medications may affect food cravings and behavior. Want to get even more jacked? Grab the RP Hypertrophy App for your training, and maximize your gym efforts with the RP Diet Coach App to nail your nutrition. Dr. Eric Trexler's Links: Instagram: https://www.instagram.com/trexlerfitness/ ResearchGate: https://www.researchgate.net/profile/Eric-Trexler MASS Research Review: https://massresearchreview.com/ 00:00:00 Intro and football banter 00:03:21 Why GLP-1s are everywhere 00:08:17 Dosing and tolerability 00:11:12 Oral GLP-1 options 00:17:55 Single, dual, and triple agonists 00:21:59 How much weight loss do trials show? 00:26:53 Side effects and protecting muscle 00:31:34 Health effects beyond weight loss 00:34:53 Reward, cravings, and enjoyment 00:46:05 Weight regain after stopping 00:50:42 Cost and long-term access 00:53:57 What wider access could change
Want to get even more jacked? Grab the RP Hypertrophy App for your training, and maximize your gym efforts with the RP Diet Coach App to nail your nutrition. 00:00:00 Dr. Mike returns: dieting, lifting, and jiu-jitsu 00:02:40 Mike's phone-number leak story 00:09:22 Why busy people overcomplicate fitness 00:11:54 Health measurements: what to track 00:17:00 Measuring health versus improving it 00:30:20 Two 30-minute workouts per week 00:34:30 How to structure efficient superset workouts 00:42:29 Simple nutrition: protein and vegetables 00:46:30 Adjusting meals for fat loss or maintenance 00:53:50 Business dinners, alcohol, and restaurant choices 01:00:00 Convenient protein options 01:02:25 Applying the basics to any busy schedule
Want to get even more jacked? Grab the RP Hypertrophy App for your training, and maximize your gym efforts with the RP Diet Coach App to nail your nutrition. Dr. Milo Wolf's Links: YouTube: @DrMiloWolf Instagram: @drmilowolf ResearchGate: Milo Wolf
Want to get even more jacked? Grab the RP Hypertrophy App for your training, and maximize your gym efforts with the RP Diet Coach App to nail your nutrition.