
The Mitochondrial Fix Perimenopausal Women Are Missing for Energy and Recovery
High Performance HealthShow Notes
In this episode, Angela is joined by Brad Currier from Timeline to explore why mitochondrial health may be a missing piece of the puzzle for women struggling with energy, recovery and performance in perimenopause. They discuss the role of mitophagy, the process of clearing out damaged mitochondria, and how exercise and Urolithin A work to support cellular renewal.
The conversation also reviews research showing improvements in muscle power, strength, endurance and recovery with Urolithin A supplementation, alongside Angela's personal experience of noticing a decline in energy when she stopped taking it and improvements when she restarted.
Key Takeaways
Exercise naturally supports mitochondrial renewal and mitophagy.
Mitophagy helps remove damaged mitochondria that can impair energy and recovery.
Urolithin A is the only clinically validated supplement currently shown to specifically support mitophagy.
Studies have shown improvements in muscle power, strength and endurance with Urolithin A supplementation.
Research suggests it may help reduce muscle damage and improve recovery.
Benefits develop gradually over weeks and months rather than being felt immediately.
Mitochondrial support may be particularly valuable during perimenopause when recovery often becomes slower and energy less reliable.
VALUABLE RESOURCES • Take the BioSyncing Quiz to help you understand what’s actually happening in your body and how to fix it. 👉 https://biosyncing.scoreapp.com/
More from High Performance Health
Can HRT actually help women in midlife build muscle and reduce visceral fat — or is lifestyle still doing most of the heavy lifting? In this conversation, Dr. Federica Amati explains what her research found, where HRT may be helpful, and why it should be seen as one tool rather than the main driver of body composition.
Dr. Alyssa Olenick on why cardio doesn't cause belly fat, what fasted training really does for fat loss, and how women in midlife should balance lifting, cardio and carbs.
How much protein do you really need to build muscle — and do women in perimenopause or menopause need more? In this conversation, Eric Helms breaks down the evidence behind some of the most common protein recommendations, including the widely quoted 1.6 grams per kilogram of body weight, when higher intakes may be useful, and why your starting point matters more than obsessing over a supposedly perfect number.
This episode is brought to you by Solaray
If you’re a woman in midlife and short on time, HIIT may be one of the most efficient ways to improve metabolic fitness and target visceral fat. In this conversation, Dr. Abbie Smith-Ryan breaks down the exact HIIT protocol her research group uses most often: one minute hard, one minute recovery, repeated for up to 10 rounds.