Show Notes
Link for you to vote on viral origins, https://www.youtube.com/c/Campbellteaching/communityUploaded 05-09-21US intelligence community, Unable, split on viral originshttps://www.bbc.com/news/world-us-canada-5836121118 agencies, Office of the Director of National IntelligenceTime is running out to gather evidenceWHO panelSoon, biologically impossibleThe window of opportunity for conducting this crucial inquiry is closing fastAll agencies assess that two hypotheses are plausible: natural exposure to an infected animal and a laboratory-associated incidentSeveral agenciesnatural exposure to an animal infected with it or a close progenitor virus, low confidenceOne intelligence agencymoderate confidence, that the first human infection was likely due a "laboratory-associated incident" at the Wuhan Institute of Virology, which has studied coronaviruses in bats for more than a decade.President BidenCritical information about the origins of this pandemic exists in the People's Republic of China, yet from the beginning, government officials in China have worked to prevent international investigators and members of the global public health community from accessing itThe world deserves answers, and I will not rest until we get themChinaForeign minister, anti-scienceFort Detrick hypothesishttps://www.youtube.com/c/Campbellteaching/community Endgame and exit strategyhttps://www.washingtonpost.com/politics/covid-how-will-it-end/2021/09/04/44bdd69a-fed7-11eb-a664-4f6de3e17ff0_story.htmlProfessor Monica Gandhi, University of CaliforniaI truly, truly think we are in the endgameThe cases will start plummeting in mid- to late September they mutate quickly, at a cost to themselveswe’re sort of at the peak of the pandemic because the delta variant is causing immunity like crazyDelta comes in like a hurricane, but it leaves a lot of immunity in its wakewe’re going to get itUnless you just sit in your room, you’re going to get it in your nosebut at least in this country, it will be manageableGandhi (Feb, 2020)United States would not tolerate a disease that killed 100 Americans a day; people would come together to do whatever it took to stop thatProfessor Ezekiel Emanuel, University of PennsylvaniaIn March 2020, the country back to normal around November 2021Now, It’s going to be at least spring 2022 and possibly much longer before most people are ready to resume normal activitiesProfessor Jay Bhattacharya, Stanford UniversityThe emergency phase of the disease is overNow, we need to work very hard to undo the sense of emergency. We should be treating covid as one of 200 diseases that affect peopleSigned Great Barrington Declaration (4th October 2020)https://gbdeclaration.org(With Martin Kulldorff (Harvard) and Sunetra Gupta (Oxford) Learn more about your ad choices. Visit megaphone.fm/adchoices Learn more about your ad choices. Visit megaphone.fm/adchoices
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Covid infection did not increase incidence of post-covid myocarditis or pericarditis.
List of covid (mostly BA.5) symptoms, (as of 6th October)Uploaded 06-10-22Sore throat, 66%Headache, 54%Runny nose, 53%Blocked nose, 53%Cough, no phlegm 51%Sneezing, 47%Cough with phlegm, 47%Hoarse, 43%Muscle pains / aches 31%Fatigue, 24%Dizzy, 22%Altered smell, 19%Swollen neck glands, 19%Chest pain,16%Sore eyes, 16%Earache, 15%Shortness of breath, 15%Chills or shivers,15%Loss of smell, 13%Fever, 12%Full Zoe, transparent reporthttps://console.cloud.google.com/storage/browser/covid-public-data.Professor Spector commentshttps://twitter.com/search?q=tim%20spector&src=typed_queryWhile Covid increasing still at over 221,000 daily cases- colds are rising even faster as the Zoe Health Study data shows. The pattern show the strong links with kids returning to school each year. Maybe we lost some of our cold immunity?US, 14-day trendshttps://www.nytimes.com/interactive/2021/us/covid-cases.htmlCases, down 23%Test positivity, 9.1%Hospitalized, (in hospital) 27,139, down 12%In ICUs, 3,309, down 12%Deaths, 391 (per day) down 11% Learn more about your ad choices. Visit megaphone.fm/adchoices Learn more about your ad choices. Visit megaphone.fm/adchoices
Denmark is ahead of the strategy, as usual. China latest news, not good at all.Uploaded 28-04-22Denmark https://www.sst.dk/en/english/corona-eng/status-of-the-epidemic/covid-19-updates-statistics-and-chartsPopulation, 5.9 millionCases, + 1,484Reinfections, 128Hospitalised, 733ICU, 13Ventilated, 4Deaths, 4Over 12, 2 doses, 89%Over 18, boosted, 76%DenmarkFebruary 1st First country to remove all pandemic related domestic restrictions(Virus was no longer considered a critical threat)Tyra Grove Krause, director of infection preparedness, SSILet the new wave run through the populationWith omicron, it is impossible to stop the spread of infection, even with severe restrictionshttps://www.telegraph.co.uk/world-news/2022/04/26/denmark-becomes-first-country-suspend-covid-vaccine-programme/First country to suspend Covid-19 vaccination programmeFrom May 15th May resume the programme after the summerDanish Health AuthorityVirus under controlHigh levels of vaccinationDrop in the number of new infectionsStabilising hospitalisation ratesBolette Soborg, Chief physicianWe plan to reopen the vaccination programme in the autumn. This will be preceded by a thorough professional assessment of who and when to vaccinate and with which vaccinesChinahttps://www.telegraph.co.uk/business/2022/04/26/china-got-covid-policy-wrong-millions-shunned-homegrown-vaccine/Dr Yanzhong Huang, Council on Foreign RelationsThey’re not even considering co-existence with the virus as an option right nowDr Liang Wannian, head of expert panelhuge disaster if China relaxed restrictionszero-Covid policy insurance for the 1.4 billion peopleBackground scandals2018, Changchun Changsheng, violated standards in 250,000 doses of vaccine for diphtheria, tetanus, whooping coughHong Kong dataTwo doses of Sinovac, 72% effective against severe or fatal Covid-19 for over 60sThree doses, 98%One month Chinese outbreak, 31,000 to 250,000 deaths.Professor Steve Tsang, Chatham HouseChina’s low death demonstrate clear superiority Zero-Covid is Xi's policyXi does not make mistakes and cannot be seen to make mistakesIt cannot be changed unless Xi says otherwise Learn more about your ad choices. Visit megaphone.fm/adchoices Learn more about your ad choices. Visit megaphone.fm/adchoices
Natural infection and / or vaccination? and Special report MississippiUploaded 21-08-21https://www.bbc.co.uk/news/health-58270098Delta in UKViral burden and vaccine effectiveness against new SARS-CoV-2 infections in the UK https://www.ndm.ox.ac.uk/covid-19/covid-19-infection-survey/results/new-studieshttps://www.ndm.ox.ac.uk/files/coronavirus/covid-19-infection-survey/finalfinalcombinedve20210816.pdfDelta infections after two vaccine doses had similar peak levels of virus to those in unvaccinated peopleTwo doses of either vaccine, same level of protection against infection as natural infectionNatural infection followed by vaccination, even more protection than vaccination aloneAfter four to five months, effectiveness of these two vaccines similarThe time between doses does not affect effectiveness in preventing new infectionsNowLevels of immunity in the communityImplications for vaccination in childrenShould we use virus or booster shots to top up immunity in adults?Prof Eleanor Riley, immunologist, University of EdinburghWe could be digging ourselves into a hole, for a very long time, where we think we can only keep Covid away by boosting every yearProf Adam Finn, government vaccine adviserOver-vaccinating people when other parts of the world had nonea bit insane, it's not just inequitable, it's stupidhttps://www.nature.com/articles/s41401-020-0485-4SARS-CoV-2 belongs to the β coronavirus familySeventh known coronavirus to infect humansFour cause colds, 229E, NL63, OC43, and HKU1SARS-CoV, 2002MERS-CoV, 2012SARS-CoV-2, 2019SARS-CoV-2Single-stranded RNA-enveloped virusEntire genome, 29,881 basesEncoding 9,860 amino acids28 proteins essential for infectionBreadth of immunityHow much of the virus the immune system learns to attackNatural infection, more polyclonalModerna or Pfizer or Oxford-AstraZeneca, just spike proteinKeeps people out of hospital28 proteins recognised give Lymphocytes a ‘target rich environment’Prof Eleanor Riley, immunologist, University of EdinburghThat means if you had a real humdinger of an infection, you may have better immunity to any new variants that pop up as you have immunity to more than just spikeStrength of immunityPower to prevent infection and cause severe diseaseIn the case of breakthrough infection or reinfectionAsymptomatic, low levels of antibodiesSymptomatic or ill, higher levels of antibodiesDuration of immunityNaturally enhanced neutralizing breadth against SARS-CoV-2 one year after infectionhttps://www.nature.com/articles/s41586-021-03696-9Natural infection, no vaccinationAntibody to the receptor binding domain, activeRBD-specific memory B cells, active and relatively stable between 6 and 12 months after infectionVaccination further increases all components of the humoral responseResults in serum neutralizing activities against variants of concernSimilar to or greater than the neutralizing activity against the original Wuhan Hu-1 strainachieved by vaccination of naive individualsThe data suggest that immunity in convalescent individuals will be very long lasting and that convalescent individuals who receive available mRNA vaccines will produce antibodies and memory B cells that should be protective against circulating SARS-CoV-2 variants.Anatomical location of immunityImmunoglobulin A, mucous membranesImmunoglobulin M and G, in the bloodProf Paul Klenerman, University of OxfordThe location of an infection makes a difference even if it's the same virus,so we would expect important differences between natural infection and vaccinesCurrent questionsDo vaccinated adults need to be boosted, or is exposure to the virus enough?Do children need vaccinating at all, or does a lifetime of ongoing exposures build a good immune defence? Immune top ups occur with respirat Learn more about your ad choices. Visit megaphone.fm/adchoices